Origins and mechanisms leading to aneuploidy in human eggs
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DOI: 10.1002/pd.5927
Abstract: The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than 40% of eggs in women at both ends… read more here.
Keywords: origins mechanisms; human eggs; aneuploidy human; leading aneuploidy ... See more keywords
Mechanisms of Aneuploidy in Human Eggs.
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DOI: 10.1016/j.tcb.2016.09.002
Abstract: Eggs and sperm develop through a specialized cell division called meiosis. During meiosis, the number of chromosomes is reduced by two sequential divisions in preparation for fertilization. In human female meiosis, chromosomes frequently segregate incorrectly,… read more here.
Keywords: human eggs; meiosis; aneuploidy human; mechanisms aneuploidy ... See more keywords
The role of ATP in the differential ability of Sr2+ to trigger Ca2+ oscillations in mouse and human eggs
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DOI: 10.1093/molehr/gaaa086
Abstract: Abstract At fertilization in mice and humans, the activation of the egg is caused by a series of repetitive Ca2+ oscillations which are initiated by phospholipase-C(zeta)ζ that generates inositol-1,4,5-trisphophate (InsP3). Ca2+ oscillations and egg activation… read more here.
Keywords: mouse eggs; human eggs; ca2 oscillations; sr2 ... See more keywords