Articles with "human embryonic" as a keyword



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Three‐Dimensional Printing of Archived Human Fetal Material for Teaching Purposes

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Published in 2019 at "Anatomical Sciences Education"

DOI: 10.1002/ase.1805

Abstract: The practical aspect of human developmental biology education is often limited to the observation and use of animal models to illustrate developmental anatomy. This is due in part to the difficulty of accessing human embryonic… read more here.

Keywords: three dimensional; anatomy; dimensional printing; material ... See more keywords
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Development of an organotypic stem cell model for the study of human embryonic palatal fusion.

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Published in 2018 at "Birth defects research"

DOI: 10.1002/bdr2.1394

Abstract: BACKGROUND Cleft palate (CP) is a common birth defect, occurring in an estimated 1 in 1,000 births worldwide. The secondary palate is formed by paired palatal shelves, consisting of a mesenchymal core with an outer… read more here.

Keywords: palatal; embryonic palatal; palatal fusion; fusion ... See more keywords
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Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies.

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Published in 2018 at "Biotechnology and bioengineering"

DOI: 10.1002/bit.26552

Abstract: Previously, it was inferred that a high glutamine synthetase (GS) activity in human embryonic kidney (HEK) 293E cells results in elevated resistance to methionine sulfoximine (MSX) and consequently hampers GS-mediated gene amplification and selection by… read more here.

Keywords: glutamine synthetase; 293e cells; embryonic kidney; hek293e ... See more keywords
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Cell‐surface contacts determine volume and mechanical properties of human embryonic kidney 293 T cells

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Published in 2022 at "Cytoskeleton"

DOI: 10.1002/cm.21735

Abstract: Alterations in the organization of the cytoskeleton precede the escape of adherent cells from the framework of cell–cell and cell‐matrix interactions into suspension. With cytoskeletal dynamics being linked to cell mechanical properties, many studies elucidated… read more here.

Keywords: cell; embryonic kidney; surface; volume ... See more keywords
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Endotoxin modulates the electrophysiological characteristics of human embryonic stem cell‐differentiated cardiomyocytes

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Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.27251

Abstract: Gram‐negative bacteria‐induced infections result in fever, arrhythmia, and even death. Lipopolysaccharide (LPS), a constituent of bacteria, leads to an inflammatory response under sepsis and increase arrhythmogenesis. This study analyzed the effects on human embryonic stem… read more here.

Keywords: channel current; channel; embryonic stem; cell ... See more keywords
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Directed Differentiation of Human Embryonic Stem Cells Toward Placode‐Derived Spiral Ganglion‐Like Sensory Neurons

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Published in 2017 at "Stem Cells Translational Medicine"

DOI: 10.1002/sctm.16-0032

Abstract: The ability to generate spiral ganglion neurons (SGNs) from stem cells is a necessary prerequisite for development of cell‐replacement therapies for sensorineural hearing loss. We present a protocol that directs human embryonic stem cells (hESCs)… read more here.

Keywords: medicine; embryonic stem; spiral ganglion; stem ... See more keywords
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Embryoid Bodies-Based Multilineage Differentiation of Human Embryonic Stem Cells Grown on Feeder-Free Conditions.

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Published in 2021 at "Methods in molecular biology"

DOI: 10.1007/7651_2021_440

Abstract: Human embryonic stem cells (hESCs) can differentiate into any cell lineage (pluripotency potential) derived from the three germ layers: ectoderm, mesoderm, and endoderm. Pluripotency is usually demonstrated in vitro by spontaneous differentiation of hESCs grown… read more here.

Keywords: embryoid bodies; embryonic stem; differentiation; stem ... See more keywords
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Human Trophectoderm Spheroid Derived from Human Embryonic Stem Cells.

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Published in 2022 at "Methods in molecular biology"

DOI: 10.1007/7651_2021_460

Abstract: The use of human embryos for studying the early implantation processes and trophoblast is restricted by ethical concerns. The development of models mimicking the peri-implantation embryos is critical for understanding the physiology of human embryos… read more here.

Keywords: derived human; human embryonic; human trophectoderm; stem cells ... See more keywords
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Cardiomyocyte Differentiation from Human Embryonic Stem Cells.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8597-5_5

Abstract: In vitro generated human cardiomyocytes hold the ultimate promise for heart patients for repair of injured or diseased myocardium, but they also provide experimental models for studying normal cardiomyocyte development, for disease modeling and for… read more here.

Keywords: differentiation human; differentiation; embryonic stem; stem cells ... See more keywords
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Rapid Differentiation of Human Embryonic Stem Cells into Testosterone-Producing Leydig Cell-Like Cells In vitro

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Published in 2021 at "Tissue Engineering and Regenerative Medicine"

DOI: 10.1007/s13770-021-00359-8

Abstract: Background: Leydig cells (LCs) are testicular somatic cells that are the major producers of testosterone in males. Testosterone is essential for male physiology and reproduction. Reduced testosterone levels lead to hypogonadism and are associated with… read more here.

Keywords: like cells; differentiation human; stem; stem cells ... See more keywords
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Gel filtration of dilute human embryonic hemoglobins reveals basis for their increased oxygen binding.

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Published in 2017 at "Analytical biochemistry"

DOI: 10.1016/j.ab.2016.12.008

Abstract: This report establishes a correlation between two known properties of the human embryonic hemoglobins-- their weak subunit assemblies as demonstrated here by gel filtration at very dilute protein concentrations and their high oxygen affinities and… read more here.

Keywords: oxygen; gel filtration; oxygen binding; filtration dilute ... See more keywords