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Published in 2019 at "Anatomical Sciences Education"
DOI: 10.1002/ase.1805
Abstract: The practical aspect of human developmental biology education is often limited to the observation and use of animal models to illustrate developmental anatomy. This is due in part to the difficulty of accessing human embryonic…
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Keywords:
three dimensional;
anatomy;
dimensional printing;
material ... See more keywords
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Published in 2018 at "Birth defects research"
DOI: 10.1002/bdr2.1394
Abstract: BACKGROUND Cleft palate (CP) is a common birth defect, occurring in an estimated 1 in 1,000 births worldwide. The secondary palate is formed by paired palatal shelves, consisting of a mesenchymal core with an outer…
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Keywords:
palatal;
embryonic palatal;
palatal fusion;
fusion ... See more keywords
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Published in 2018 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.26552
Abstract: Previously, it was inferred that a high glutamine synthetase (GS) activity in human embryonic kidney (HEK) 293E cells results in elevated resistance to methionine sulfoximine (MSX) and consequently hampers GS-mediated gene amplification and selection by…
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Keywords:
glutamine synthetase;
293e cells;
embryonic kidney;
hek293e ... See more keywords
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Published in 2022 at "Cytoskeleton"
DOI: 10.1002/cm.21735
Abstract: Alterations in the organization of the cytoskeleton precede the escape of adherent cells from the framework of cell–cell and cell‐matrix interactions into suspension. With cytoskeletal dynamics being linked to cell mechanical properties, many studies elucidated…
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Keywords:
cell;
embryonic kidney;
surface;
volume ... See more keywords
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Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27251
Abstract: Gram‐negative bacteria‐induced infections result in fever, arrhythmia, and even death. Lipopolysaccharide (LPS), a constituent of bacteria, leads to an inflammatory response under sepsis and increase arrhythmogenesis. This study analyzed the effects on human embryonic stem…
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Keywords:
channel current;
channel;
embryonic stem;
cell ... See more keywords
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Published in 2017 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.16-0032
Abstract: The ability to generate spiral ganglion neurons (SGNs) from stem cells is a necessary prerequisite for development of cell‐replacement therapies for sensorineural hearing loss. We present a protocol that directs human embryonic stem cells (hESCs)…
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Keywords:
medicine;
embryonic stem;
spiral ganglion;
stem ... See more keywords
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_440
Abstract: Human embryonic stem cells (hESCs) can differentiate into any cell lineage (pluripotency potential) derived from the three germ layers: ectoderm, mesoderm, and endoderm. Pluripotency is usually demonstrated in vitro by spontaneous differentiation of hESCs grown…
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Keywords:
embryoid bodies;
embryonic stem;
differentiation;
stem ... See more keywords
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Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_460
Abstract: The use of human embryos for studying the early implantation processes and trophoblast is restricted by ethical concerns. The development of models mimicking the peri-implantation embryos is critical for understanding the physiology of human embryos…
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Keywords:
derived human;
human embryonic;
human trophectoderm;
stem cells ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8597-5_5
Abstract: In vitro generated human cardiomyocytes hold the ultimate promise for heart patients for repair of injured or diseased myocardium, but they also provide experimental models for studying normal cardiomyocyte development, for disease modeling and for…
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Keywords:
differentiation human;
differentiation;
embryonic stem;
stem cells ... See more keywords
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Published in 2021 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-021-00359-8
Abstract: Background: Leydig cells (LCs) are testicular somatic cells that are the major producers of testosterone in males. Testosterone is essential for male physiology and reproduction. Reduced testosterone levels lead to hypogonadism and are associated with…
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Keywords:
like cells;
differentiation human;
stem;
stem cells ... See more keywords
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Published in 2017 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2016.12.008
Abstract: This report establishes a correlation between two known properties of the human embryonic hemoglobins-- their weak subunit assemblies as demonstrated here by gel filtration at very dilute protein concentrations and their high oxygen affinities and…
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Keywords:
oxygen;
gel filtration;
oxygen binding;
filtration dilute ... See more keywords