A three-dimensional analysis of cranial nerve development in human embryos.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical anatomy"
DOI: 10.1002/ca.23889
Abstract: INTRODUCTION To increase our understanding of the etiology of specific neurological disorders (e.g., Duane syndrome, glossoptosis in Pierre Robin sequence), proper knowledge of anatomy and embryology of cranial nerves is necessary. We investigated cranial nerve… read more here.
Keywords: cranial nerves; development; human embryos; nerve development ... See more keywords
Effect of Mechanical Microvibration on the Quality of Human Embryos during In Vitro Culturing and Outcomes of Assisted Reproduction Technologies
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4211-x
Abstract: We summarized the data on the role and efficiency of mechanical microvibration during embryo culturing in assisted reproduction protocols. The efficiency of culturing systems with microvibration in assisted reproduction programs and possible mechanisms of microvibration… read more here.
Keywords: human embryos; mechanical microvibration; effect; assisted reproduction ... See more keywords
From the flexible to the complex: carving the zygotic pie into operational pieces
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-021-02360-5
Abstract: In his prescient two-decade old editorial entitled “What only the embryo knows,” the late Stephen Jay Gould credits Karl Ernst von Baer for more than having discovered the mammalian egg in 1827. Besides publishing the… read more here.
Keywords: human embryos; carving zygotic; flexible complex; mass ... See more keywords
Mutational Processes Shaping the Genome in Early Human Embryos
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.02.008
Abstract: In-vitro-fertilized human embryos often acquire large structural and numerical chromosomal abnormalities. Liu et al. now show that multiple smaller copy number variations may also arise in in-vivo-conceived embryos. Analysis of these variations provides insight into the… read more here.
Keywords: human embryos; early human; shaping genome; genome early ... See more keywords
The relationship between preimplantation morphokinetics of human embryos and sex chromosome pattern.
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive biology"
DOI: 10.1016/j.repbio.2018.10.002
Abstract: The aim of this study was to determine the relationship between the gender of human embryos and chronological changes during the two pronuclear (2PN) embryonic stage and blastocyst formation on day five after injection using… read more here.
Keywords: human embryos; relationship preimplantation; preimplantation; embryos value ... See more keywords
Temporal and spatial development of intestinal smooth muscle layers of human embryos and fetuses
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000253
Abstract: Abstract The sequential occurrence of three layers of smooth muscle layers (SML) in human embryos and fetus is not known. Here, we investigated the process of gut SML development in human embryos and fetuses and… read more here.
Keywords: gut; human embryos; sml; gestation ... See more keywords
Hybrid zoo: Introducing pig–human embryos and a rat–mouse
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature.2017.21378
Abstract: Chimaeras could pave the way for growing human organs in other animals. read more here.
Keywords: hybrid zoo; human embryos; zoo introducing; pig human ... See more keywords
Human cleaving embryos enable efficient mitochondrial base-editing with DdCBE
Sign Up to like & getrecommendations! Published in 2022 at "Cell Discovery"
DOI: 10.1038/s41421-021-00372-0
Abstract: Dear Editor, Mitochondrial diseases could be caused by heritable mutations in both mtDNA and nuclear DNA. Because mitochondria membrane insulated mtDNAs’ access from large ribonucleoprotein complex of Cas9 and sgRNA, mtDNAs are intractable for genetic… read more here.
Keywords: human embryos; embryos; conversion; ddcbe ... See more keywords
Deciphering human macrophage development at single-cell resolution
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2316-7
Abstract: Macrophages are the first cells of the nascent immune system to emerge during embryonic development. In mice, embryonic macrophages infiltrate developing organs, where they differentiate symbiotically into tissue-resident macrophages (TRMs) 1 . However, our understanding… read more here.
Keywords: single cell; macrophage development; human embryos; development ... See more keywords
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Sign Up to like & getrecommendations! Published in 2021 at "Nature genetics"
DOI: 10.1038/s41588-021-00818-x
Abstract: Characterization of the progression of cellular states during human embryogenesis can provide insights into the origin of pediatric diseases. We examined the transcriptional states of neural crest- and mesoderm-derived lineages differentiating into adrenal glands, kidneys,… read more here.
Keywords: single cell; human embryos; embryos identifies; cell transcriptomics ... See more keywords
New protocol based on massive parallel sequencing for aneuploidy screening of preimplantation human embryos
Sign Up to like & getrecommendations! Published in 2017 at "Systems Biology in Reproductive Medicine"
DOI: 10.1080/19396368.2017.1312633
Abstract: ABSTRACT Novel next-generation sequencing procedures have rapidly emerged into the preimplantation genetic screening framework. This work presents the design and validation of a new low-coverage whole-genome sequencing assay for aneuploidy detection in single blastomeres and… read more here.
Keywords: human embryos; new protocol; based massive; preimplantation ... See more keywords