Sclerostin stimulates angiogenesis in human endothelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Bone"
DOI: 10.1016/j.bone.2017.03.001
Abstract: Sclerostin, negative regulator of bone formation, has been originally known as an osteocyte product. Recently, it has been also detected in hypertrophic chondrocytes, distinctive cells of avascular cartilage which is invaded by capillaries and then… read more here.
Keywords: human endothelial; sclerostin; angiogenesis human; sclerostin stimulates ... See more keywords
Cytotoxicity mechanisms of nitrogen-doped graphene obtained by electrochemical exfoliation of graphite rods, on human endothelial and colon cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Carbon"
DOI: 10.1016/j.carbon.2019.12.011
Abstract: Abstract Three nitrogen-doped graphene samples were synthesized by electrochemical exfoliation of graphite rods via pulses of current. Depending on the synthesis conditions, the samples had different content of nitrogen (0.79, 2.56 and 2.33 wt%) and were… read more here.
Keywords: nitrogen; colon cancer; human endothelial; cancer cells ... See more keywords
miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2017.10.001
Abstract: The role of microRNAs in controlling angiogenesis is recognized as a promising therapeutic target in both cancer and cardiovascular disorders. However, understanding a miRNA's pleiotropic effects on angiogenesis is a limiting factor for these types… read more here.
Keywords: human endothelial; mir 200b; endothelial cells; hypoxia ... See more keywords
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2016.12.033
Abstract: Abstract The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative stress and inflammation were investigated in TNF-α-activated human endothelial cells. HTyr sulfate metabolites decreased reactive oxygen species and prevented… read more here.
Keywords: human endothelial; stress inflammation; inflammation; endothelial cells ... See more keywords
Glycocalyx sialic acids regulate Nrf2-mediated signaling by fluid shear stress in human endothelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101816
Abstract: Activation of the nuclear factor erythroid 2–related factor 2 (Nrf2) pathway is critical for vascular endothelial redox homeostasis in regions of high, unidirectional shear stress (USS), however the underlying mechanosensitive mediators are not fully understood.… read more here.
Keywords: sialic acids; sia; human endothelial; shear stress ... See more keywords
Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42127
Abstract: Human endothelial cells (ECs) are widely used to study mechanisms of angiogenesis, inflammation, and endothelial permeability. Targeted gene disruption induced by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR-Associated Protein 9 (Cas9) nuclease gene editing is… read more here.
Keywords: disruption; human endothelial; endothelial cells; primary human ... See more keywords
MO017THERAPEUTICAL POTENTIAL OF ENZYME REPLACEMENT: NEW INSIGHTS AND PERSPECTIVES IN HUMAN ENDOTHELIAL CELLS TREATED WITH CHLOROQUINE
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab079.0013
Abstract: Abstract Background and Aims COVID-19 is a pandemic with no end in sight. There is only one approved antiviral agent but global stocks are deemed insufficient. Despite in vitro antiviral activity, clinical trials of chloroquine… read more here.
Keywords: enzyme replacement; human endothelial; endothelial cells; chloroquine ... See more keywords
Resveratrol inhibits VEGF‐induced angiogenesis in human endothelial cells associated with suppression of aerobic glycolysis via modulation of PKM2 nuclear translocation
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13017
Abstract: Endothelial cells (ECs) mainly depend on aerobic glycolysis to generate angiogenesis. Deregulation of glycolysis is often observed in human endothelial cells during angiogenesis. In the present study, we first report that resveratrol (RST), which has… read more here.
Keywords: glycolysis; angiogenesis; aerobic glycolysis; human endothelial ... See more keywords
IL‐36γ has proinflammatory effects on human endothelial cells
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Dermatology"
DOI: 10.1111/exd.13228
Abstract: Interleukin‐36 cytokines are predominantly expressed by epithelial cells. Significant upregulation of epidermal IL‐36 is now a recognised characteristic of psoriatic skin inflammation. IL‐36 is known to induce inflammatory responses in dendritic cells, fibroblasts and epithelial… read more here.
Keywords: dermatology; human endothelial; proinflammatory effects; endothelial cells ... See more keywords
Analysis of Metabolite Profiling in Human Endothelial Cells after Plasma Jet Treatment
Sign Up to like & getrecommendations! Published in 2019 at "BioMed Research International"
DOI: 10.1155/2019/3015150
Abstract: Cold atmospheric plasma (CAP) is a novel technology, which has been widely applied in biomedicine, especially in wound healing, dermatological treatment, hemostasis, and cancer treatment. In most cases, CAP treatment will interact with innumerable blood… read more here.
Keywords: human endothelial; analysis; treatment; plasma treatment ... See more keywords
Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0190374
Abstract: Quercetin has been reported to act as a senolytic by selectively removing senescent endothelial cells, and thus it would seem quercetin could revolutionize the field of gerontology. However, given quercetin's narrow therapeutic index reported in… read more here.
Keywords: adult human; human endothelial; senescent cells; endothelial cells ... See more keywords