Transcytosis of IgA Attenuates Salmonella Invasion in Human Enteroids and Intestinal Organoids
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00041-22
Abstract: Secretory IgA (SIgA) is the most abundant antibody type in intestinal secretions where it contributes to safeguarding the epithelium from invasive pathogens like the Gram-negative bacterium, Salmonella enterica serovar Typhimurium (STm). For example, we recently… read more here.
Keywords: iga; sal4; siga; human enteroids ... See more keywords
Human milk extracellular vesicles protect protein cargo from human digestion and are taken up by neonatal human enteroids
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733311
Abstract: Background: Human milk (HM) is the ideal infant nutrition and reduces infant death and disease. For example, HM is the best-known preventative for the deadly neonatal intestinal inflammatory disease, necrotizing enterocolitis (NEC), for which there… read more here.
Keywords: cargo; physiology; protein cargo; human enteroids ... See more keywords
Neonatal Human Enteroids Take Up Human Milk Extracellular Vesicles That Survive Neonatal Human Digestion
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.699
Abstract: Background: Human milk (HM) is the ideal infant nutrition and reduces infant death and disease. HM contains thousands of bioactive components, including extracellular vesicles (HMEVs). HMEVs are lipid bilayer-encased nanoparticles released from mammary epithelial cells… read more here.
Keywords: survive neonatal; physiology; human enteroids; human milk ... See more keywords