Comprehensive characterization and simultaneous analysis of overall lipids in reconstructed human epidermis using NPLC/HR-MSn: 1-O-E (EO) Cer, a new ceramide subclass
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02301-3
Abstract: Stratum corneum lipids are responsible for the skin’s barrier function. They are the final product of epidermis lipid biosynthesis. During this process, lipids evolve from simple to complex structures in three main levels respectively (stratum… read more here.
Keywords: nplc msn; human epidermis; comprehensive characterization; epidermis ... See more keywords
Immortalized equivalent human epidermis as a platform to evaluation hair dyes toxicity: Efficiency comparison between 3D and monolayer culture.
Sign Up to like & getrecommendations! Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.109227
Abstract: The use of 3D models in various scientific applications is becoming more popular to replace traditional monolayers models. In this work, we used a three-dimensional in-house model of epidermis using HaCaT immortalized cells to evaluate… read more here.
Keywords: monolayer; hair; toxicity; model ... See more keywords
Oligomeric α-Synuclein induces skin degeneration in reconstructed human epidermis
Sign Up to like & getrecommendations! Published in 2022 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2022.02.010
Abstract: Aged and photoaged skin exhibit fine wrinkles that are signs of epidermal inflammation and degeneration. It has been shown that healthy elderly skin expresses amyloidogenic proteins, including α-Synuclein, which are known to oligomerize and trigger… read more here.
Keywords: degeneration; synuclein; degeneration reconstructed; oligomeric synuclein ... See more keywords
Modeling dermatophytosis in reconstructed human epidermis: A new tool to study infection mechanisms and to test antifungal agents
Sign Up to like & getrecommendations! Published in 2017 at "Medical Mycology"
DOI: 10.1093/mmy/myw111
Abstract: &NA; Dermatophytosis is a superficial fungal infection of keratinized structures that exhibits an increasing prevalence in humans and is thus requesting novel prophylactic strategies and therapies. However, precise mechanisms used by dermatophytes to adhere at… read more here.
Keywords: modeling dermatophytosis; fungal infection; infection; human epidermis ... See more keywords
Particulate matter 2.5 induced hyperpigmentation in reconstructed human epidermis model (MelaKutis®)
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001934
Abstract: To the Editor: Epidemiological studies have confirmed Biocell Biotechnology), and NHEMs in Medium 254 that fine particulate matter (PM2.5) is related to skin hyperpigmentation, but experimental evidence is lacking. Here, we used normal human epidermal… read more here.
Keywords: reconstructed human; particulate matter; human epidermis; hyperpigmentation ... See more keywords
Roseomonas cutis sp. nov., isolated from human epidermis.
Sign Up to like & getrecommendations! Published in 2025 at "International journal of systematic and evolutionary microbiology"
DOI: 10.1099/ijsem.0.006617
Abstract: Five pink-pigmented bacterial strains, isolated from human skin and classified within the genus Roseomonas, were examined. Among them, four were identified as Roseomonas mucosa, while strain OT10T was deemed to be a potential novel species.… read more here.
Keywords: human epidermis; roseomonas cutis; isolated human; cutis nov ... See more keywords
Reproducing the scalp microbiota community: co‐colonization of a 3D reconstructed human epidermis with C. acnes and M. restricta
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Cosmetic Science"
DOI: 10.1111/ics.12688
Abstract: A 3D reconstructed human epidermis (RHE) model colonized with specific microbial strains was developed to model the complex interactions between strains of the human scalp hair. read more here.
Keywords: reproducing scalp; microbiota community; human epidermis; scalp microbiota ... See more keywords
Probing skin photoallergens in reconstructed human epidermis: An EPR spin trapping investigation
Sign Up to like & getrecommendations! Published in 2024 at "Photochemistry and Photobiology"
DOI: 10.1111/php.14010
Abstract: Photoallergic contact dermatitis is a skin disease caused by combined exposure to photoreactive chemicals and sunlight. Exposure to allergens and the risk of skin sensitization is an essential regulatory issue within the industry. Yet, only… read more here.
Keywords: spin trapping; human epidermis; probing skin; reconstructed human ... See more keywords
Noninvasive evaluation of the skin barrier in reconstructed human epidermis using speckle analysis: Correlation with Raman microspectroscopy
Sign Up to like & getrecommendations! Published in 2024 at "Skin Research and Technology"
DOI: 10.1111/srt.13708
Abstract: Reconstructed epidermis models, obtained from 3D keratinocytes culture, have gained significant prominence as prototypes for safety and efficacy testing in skin research. To effectively evaluate these models, it is essential to perform molecular and functional… read more here.
Keywords: barrier reconstructed; human epidermis; barrier; evaluation skin ... See more keywords
Probing the human epidermis by combining ToF-SIMS and multivariate analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Biointerphases"
DOI: 10.1116/6.0002289
Abstract: The mammalian organism is continuously exposed to various biological and chemical threats from its surroundings. In order to provide protection against these threats, mammals have developed a specialized defense system at the interface with their… read more here.
Keywords: tof; methodology; tof sims; human epidermis ... See more keywords
Evaluating blue light impact on reconstructed human epidermis using laser speckle imaging
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.30.5.056001
Abstract: Abstract. Significance Blue light exposure is ubiquitous in modern life, raising concerns about its potential impact on skin health. Aim We aim to explore the effects of blue light on the reconstructed human epidermis (RHE)… read more here.
Keywords: human epidermis; blue light; speckle imaging; impact ... See more keywords