Dithionated Nucleobases as Effective Photodynamic Agents against Human Epidermoid Carcinoma Cells
Sign Up to like & getrecommendations! Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201800148
Abstract: Sulfur‐substituted nucleobases (i.e., thiobases) are a prospective class of compounds for clinical and cosmetic topical phototherapies. Recent investigations of several thiobases have revealed the ultrafast and efficient population of reactive triplet states upon ultraviolet‐A (UVA)… read more here.
Keywords: human epidermoid; photodynamic agents; dithionated nucleobases; epidermoid carcinoma ... See more keywords
Impaired actin filaments decrease cisplatin sensitivity via dysfunction of volume‐sensitive Cl− channels in human epidermoid carcinoma cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29767
Abstract: Cisplatin is a widely used platinum‐based anticancer drug in the chemotherapy of numerous human cancers. However, cancer cells acquire resistance to cisplatin. So far, functional loss of volume‐sensitive outwardly rectifying (VSOR) Cl− channels has been… read more here.
Keywords: human epidermoid; volume; cisplatin; epidermoid carcinoma ... See more keywords
Ribociclib Inhibits P-gp-Mediated Multidrug Resistance in Human Epidermoid Carcinoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.867128
Abstract: The efficacy of cancer chemotherapy can be attenuated or abrogated by multidrug resistance (MDR) in cancer cells. In this study, we determined the effect of the CDK4/6 inhibitor, ribociclib (or LEE011), on P-glycoprotein (P-gp)-mediated MDR… read more here.
Keywords: multidrug resistance; human epidermoid; epidermoid carcinoma; mediated mdr ... See more keywords
Peroxisome proliferator-activated receptor-γ agonist-mediated inhibition of cell growth is independent of apoptosis in human epidermoid carcinoma A431 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2018.8136
Abstract: Evidence suggests that peroxisome proliferator activated receptor-γ (PPAR-γ) acts as a tumor suppressor in multiple types of cancer; however, the role of action of PPAR-γ on human epidermoid carcinoma is unclear. The present study investigated… read more here.
Keywords: human epidermoid; apoptosis; cell growth; epidermoid carcinoma ... See more keywords