Significantly elevated serum human epididymis protein‐4 in chronic kidney disease patients without ovarian cancer: A large‐scale retrospective study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24847
Abstract: Human epididymis protein‐4 (HE‐4) is a commonly used biomarker for diagnosing ovarian cancer. Elevated HE‐4 has also been observed in various benign conditions including chronic kidney disease (CKD); however, generalizability and statistical power of previous… read more here.
Keywords: epididymis protein; ovarian cancer; chronic kidney; human epididymis ... See more keywords
Sensitive amperometric immunosensor with improved electrocatalytic Au@Pd urchin-shaped nanostructures for human epididymis specific protein 4 antigen detection.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2019.04.023
Abstract: Sensitive detection of early ovarian cancer is imminent for women's health. Human epididymis specific protein 4 antigen (HE4 Ag), as a novel tumor marker, has good specificity and sensitivity in ovarian cancer markers, especially for… read more here.
Keywords: protein antigen; immunosensor; epididymis specific; human epididymis ... See more keywords
Targeting and neutralizing human epididymis protein 4 by novel nanobodies to suppress ovarian cancer cells and attenuate cisplatin resistance.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.01.015
Abstract: Human epididymis protein 4 (HE4) is a glycoprotein secreted by epithelial ovarian cancer (EOC) cells and is a novel and specific biomarker for diagnosing and prognosing EOC. Previous studies have shown that overexpression of HE4… read more here.
Keywords: epididymis protein; human epididymis; he4; anti he4 ... See more keywords
Human epididymis protein 4 is associated with severity and poor prognosis of connective tissue disease-associated interstitial lung disease with usual interstitial pneumonia pattern.
Sign Up to like & getrecommendations! Published in 2022 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2022.108704
Abstract: BACKGROUND Overexpression of human epididymis protein 4 (HE4) was previously described in idiopathic pulmonary fibrosis (IPF), but whether serum HE4 can be considered as a potential biomarker in connective tissue disease-associated interstitial lung disease (CTD-ILD)… read more here.
Keywords: uip ctd; lung; human epididymis; disease ... See more keywords
Prognostic values of human epididymis protein 4 expression in patients with endometrial cancer: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.15356
Abstract: There is no consensus on the correlation between human epididymis protein 4 (HE4) and prognosis of endometrial cancer (EC). Therefore, we performed a meta‐analysis to assess the relationship between HE4 and prognosis of EC. read more here.
Keywords: endometrial cancer; epididymis protein; meta analysis; human epididymis ... See more keywords
Region-specific microRNA signatures in the human epididymis
Sign Up to like & getrecommendations! Published in 2018 at "Asian Journal of Andrology"
DOI: 10.4103/aja.aja_40_18
Abstract: The epithelium of the human epididymis maintains an appropriate luminal environment for sperm maturation that is essential for male fertility. Regional expression of small noncoding RNAs such as microRNAs contributes to segment-specific gene expression and… read more here.
Keywords: specific microrna; region specific; human epididymis; expression ... See more keywords