Human ERG oncoprotein represses a Drosophila LIM domain binding protein-coding gene Chip.
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DOI: 10.1073/pnas.2211189119
Abstract: Human ETS Related Gene, ERG, a master transcription factor, turns oncogenic upon its out-of-context activation in diverse developmental lineages. However, the mechanism underlying its lineage-specific activation of Notch (N), Wnt, or EZH2-three well-characterized oncogenic targets… read more here.
Keywords: represses drosophila; lim domain; erg; domain binding ... See more keywords