Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short- and Long-Lived Radicals.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202502621
Abstract: Metallofullerenols (MFs), functionalized endohedral fullerenes, exhibit unique activity by integrating atomic, molecular, and supramolecular levels of matter organization. The antioxidant properties of MFs constitute a novel technology, utilizing these nanocompounds for radioprotection. This integration of… read more here.
Keywords: sc3n c80; radiation induced; damage; human erythrocytes ... See more keywords
Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma membrane redox system
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-018-04062-5
Abstract: Mercury is among the most toxic heavy metals and a widespread environmental pollutant. Mercury chloride (HgCl2) is an inorganic compound of mercury which is easily absorbed in the gastrointestinal tract and then enters the blood… read more here.
Keywords: hemoglobin oxidation; mercury chloride; hgcl2; human erythrocytes ... See more keywords
Di-n-butyl phthalate, butylbenzyl phthalate and their metabolites induce haemolysis and eryptosis in human erythrocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.03.161
Abstract: Phthalates have been extensively used as plasticizers in various fields, including food, cosmetic, and pharmaceutical industry. Those compounds do not form covalent bonds to substances they are being added to, and thus they may migrate… read more here.
Keywords: phthalate; butyl phthalate; butylbenzyl phthalate; eryptosis ... See more keywords
In vitro effects of benzimidazole/thioether-copper complexes with antitumor activity on human erythrocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2017.10.009
Abstract: Two cytotoxic copper(II) complexes with N-H and N-methylated benzimidazole-derived ligands (Cu-L1 and Cu-L1Me; L1=bis(2-methylbenzimidazolyl)(2-methylthioethyl)amine, L1Me=bis(1-methyl-2-methylbenzimidazolyl)(2-methylthioethyl)amine) were synthesized and exposed to human erythrocytes and molecular models of its membrane. The latter were bilayers built-up of dimyristoylphosphatidylcholine… read more here.
Keywords: copper complexes; microscopy; vitro effects; l1me ... See more keywords
Dietary supplementation with annatto food-coloring extracts increases the resistance of human erythrocytes to hemolysis.
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition research"
DOI: 10.1016/j.nutres.2020.02.003
Abstract: Erythrocytes exhibit high susceptibility to hemolysis in several pathologies due to the oxidation of cellular components. We hypothesized that annatto carotenoids improve the redox status of erythrocyte plasma membranes and promote a consequent increase in… read more here.
Keywords: supplementation; hemolysis; food; resistance ... See more keywords
Thiram-induced cytotoxicity and oxidative stress in human erythrocytes: an in vitro study.
Sign Up to like & getrecommendations! Published in 2020 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2019.12.003
Abstract: Tetramethylthiuram disulfide, commonly known as thiram, is an organosulfur compound which is used as a bactericide, fungicide and ectoparasiticide to prevent disease in seeds and crops. Being a fungicide there is a high probability of… read more here.
Keywords: thiram; induced cytotoxicity; human erythrocytes; thiram induced ... See more keywords
Redox regulation of nitrosyl-hemoglobin in human erythrocytes
Sign Up to like & getrecommendations! Published in 2019 at "Redox Biology"
DOI: 10.1016/j.redox.2019.101399
Abstract: Oxidative stress perturbs vascular homeostasis leading to endothelial dysfunction and cardiovascular diseases. Vascular reactive oxygen species (ROS) reduce nitric oxide (NO) bioactivity, a hallmark of cardiovascular and metabolic diseases. We measured steady-state vascular NO levels… read more here.
Keywords: state; hbno; redox regulation; steady state ... See more keywords
Proof of Concept: Protein Delivery into Human Erythrocytes Using Stable Cavitation.
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DOI: 10.1021/acs.molpharmaceut.1c00907
Abstract: Human erythrocytes represent candidates of choice as carriers for a wide range of drugs due to their unique biophysical and physiological properties. In this study, we used a sonoporation device generating and monitoring acoustic stable… read more here.
Keywords: protein delivery; delivery human; human erythrocytes; cavitation ... See more keywords
Biophysical and structural modifications on human erythrocytes induced by ethanolic extracts of Ruta graveolens, Artemisia ludoviciana, and Lippia graveolens: a study by ATR-FTIR spectroscopy
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DOI: 10.1039/d5ra06459g
Abstract: By using ATR-FTIR spectroscopy and spectral deconvolution analysis, biophysical and structural modifications induced by ethanolic extracts of Rutta graveolens, Artemisia ludoviciana, and Lippia graveolens (commonly used as medicinal plants) on human erythrocytes were investigated. The… read more here.
Keywords: spectroscopy; artemisia ludoviciana; human erythrocytes; atr ftir ... See more keywords
Lysis of human erythrocytes due to Piezo1-dependent cytosolic calcium overload as a mechanism of circulatory removal
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2407765121
Abstract: Significance Mature red blood cells (RBC) are enucleated, devoid of cell organelles, and incapable of translational activity. Yet, the RBC lifespan is remarkably consistent, and the molecular underpinnings of this apparently timely and targeted removal… read more here.
Keywords: due piezo1; calcium; human erythrocytes; lysis ... See more keywords
Impact of drying processes on Bryophyllum pinnatum phenolic constituents and its anti-inflammatory and antioxidative activities in human erythrocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13298
Abstract: The effect of drying on the phytoconstituents, antioxidative, and anti-inflammatory properties of Bryophyllum pinnatum leaves was investigated. The phenolic constituents were characterized using HPLC-DAD. The aqueous extraction was done and various assays (Inhibition of membrane… read more here.
Keywords: anti inflammatory; bryophyllum pinnatum; phenolic constituents; freeze dried ... See more keywords