Human ESC-Derived Cardiomyocytes Restore Function in Infarcted Hearts of Non-Human Primates
Sign Up to like & getrecommendations! Published in 2018 at "Nature biotechnology"
DOI: 10.1038/nbt.4162
Abstract: Pluripotent stem cell–derived cardiomyocyte grafts can remuscularize substantial amounts of infarcted myocardium and beat in synchrony with the heart, but in some settings cause ventricular arrhythmias. It is unknown whether human cardiomyocytes can restore cardiac… read more here.
Keywords: restore function; derived cardiomyocytes; cardiomyocytes restore; esc derived ... See more keywords
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner.
Sign Up to like & getrecommendations! Published in 2023 at "Protein & cell"
DOI: 10.1093/procel/pwad027
Abstract: Hypoxia-inducible factor (HIF-1α), a core transcription factor responding to changes in cellular oxygen levels, is closely associated with a wide range of physiological and pathological conditions. However, its differential impacts on vascular cells types and… read more here.
Keywords: regeneration; cell; vascular cells; human esc ... See more keywords