How do elevated levels of testosterone affect the function of the human fallopian tube and fertility?—New insights
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23291
Abstract: Excess testosterone levels affect up to 20% of the female population worldwide and are a key component in the pathogenesis of polycystic ovary syndrome. However, little is known about how excess testosterone affects the function… read more here.
Keywords: elevated levels; levels testosterone; function human; fallopian tube ... See more keywords
B cell activation factor (BAFF) induces inflammation in the human fallopian tube leading to tubal pregnancy
Sign Up to like & getrecommendations! Published in 2019 at "BMC Pregnancy and Childbirth"
DOI: 10.1186/s12884-019-2324-5
Abstract: BackgroundTubal pregnancy is recognized as one of the most common ectopic pregnancy types. Salpingitis may result in tubal pregnancy by causing fallopian tube occlusion and hydrosalpinx. B cell activation factor (BAFF) is a proinflammatory cytokine… read more here.
Keywords: tubal pregnancy; pregnancy; fallopian tube; inflammation human ... See more keywords
Increased Local Testosterone Levels Alter Human Fallopian Tube mRNA Profile and Signaling
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DOI: 10.3390/cancers15072062
Abstract: Simple Summary Increased testosterone has been associated with increased risk of ovarian cancer. High Grade Serous Ovarian Carcinoma (HGSOC) mostly originates from the fallopian tube epithelium (FTE), however, the stepwise events that occur during its… read more here.
Keywords: human fallopian; ovarian cancer; fallopian tube; testosterone ... See more keywords
Spontaneous Transformation of a p53 and Rb-Defective Human Fallopian Tube Epithelial Cell Line after Long Passage with Features of High-Grade Serous Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213843
Abstract: Ovarian cancer is one of the most lethal gynecological cancers, and 80% are high-grade serous carcinomas (HGSOC). Despite advances in chemotherapy and the development of targeted therapies, the survival rate of HGSOC has only moderately… read more here.
Keywords: cell; high grade; grade serous; human fallopian ... See more keywords