Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
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DOI: 10.1080/19420862.2021.1893888
Abstract: ABSTRACT Albumin has a serum half-life of 3 weeks in humans. This feature can be used to improve the pharmacokinetics of shorter-lived biologics. For instance, an albumin-binding domain (ABD) can be used to recruit albumin.… read more here.
Keywords: half life; life; albumin binding; human fcrn ... See more keywords