CPHEN‐013: Comprehensive phenotyping of hematopoietic stem and progenitor cells in the human fetal liver
Sign Up to like & getrecommendations! Published in 2022 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24540
Abstract: Hematopoietic stem cells (HSCs) reside at the top of the hematopoietic hierarchy and can give rise to all the mature blood cell types in our body, while at the same time maintaining a pool of… read more here.
Keywords: fetal liver; human fetal; hematopoietic stem; stem ... See more keywords
Human Fetal Cell Therapy in Huntington's Disease: A Randomized, Multicenter, Phase II Trial
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28201
Abstract: Huntington's disease is a rare, severe, inherited neurodegenerative disease in which we assessed the safety and efficacy of grafting human fetal ganglionic eminence intrastriatally. read more here.
Keywords: cell therapy; huntington disease; human fetal; fetal cell ... See more keywords
Human fetal mesoangioblasts reveal tissue‐dependent transcriptional signatures
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0209
Abstract: Mesoangioblasts (MABs) derived from adult skeletal muscles are well‐studied adult stem/progenitor cells that already entered clinical trials for muscle regeneration in genetic diseases; however, the transcriptional identity of human fetal MABs (fMABs) remains largely unknown.… read more here.
Keywords: differentiation outcomes; human fetal; skeletal muscles; tissue ... See more keywords
Generation of Induced Dopaminergic Neurons from Human Fetal Fibroblasts.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1601-7_7
Abstract: Since the first demonstration of direct dopaminergic neuronal reprogramming, over a dozen methods have been developed to generate induced dopaminergic neurons from various sources of cells. Here, we first present an overview of the different… read more here.
Keywords: generate induced; human fetal; generation induced; induced dopaminergic ... See more keywords
Nouveaux acteurs de la différenciation gonadique normale et pathologique, approches cellules uniques chez l’Homme
Sign Up to like & getrecommendations! Published in 2021 at "Annales d'Endocrinologie"
DOI: 10.1016/j.ando.2021.07.020
Abstract: Objective Little is still known about the origin of somatic progenitor cells of human fetal gonads, their molecular identity and the transcriptional programs controlling their differentiation towards multiple fates. In this study, we performed single-cell… read more here.
Keywords: single cell; human fetal; gonad; fetal gonads ... See more keywords
Production of functional human fetal hemoglobin in Nicotiana benthamiana for development of hemoglobin-based oxygen carriers.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.06.102
Abstract: Hemoglobin based oxygen carriers (HBOCs) have long been pursued to meet clinical needs by using native hemoglobin (Hb) from human or animal blood, or recombinantly produced Hb, but the development has been impeded by safety… read more here.
Keywords: production; hemoglobin; hemoglobin based; human fetal ... See more keywords
Decellularized human fetal intestine as a bioscaffold for regeneration of the rabbit bladder submucosa.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2018.01.018
Abstract: PURPOSE We aim to report a method to create a natural acellular scaffold from human fetal small intestine for augmentation cystoplasty in rabbits. METHODS Fetal intestines were decellularized by immersion in a hypotonic solution. The… read more here.
Keywords: fetal intestine; human fetal; bladder; decellularized human ... See more keywords
Viral infection dampens human fetal membrane type I interferon responses triggered by bacterial LPS.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2020.103126
Abstract: The maternal-fetal interface possesses innate immune strategies to protect against infections. We previously reported that prior viral infection of human fetal membranes (FMs) in vitro and mouse FMs in vivo sensitized the tissue to low… read more here.
Keywords: human fetal; infection; viral infection; bacterial lps ... See more keywords
In an in-vitro model using human fetal membranes, α-lipoic acid inhibits inflammation induced fetal membrane weakening.
Sign Up to like & getrecommendations! Published in 2018 at "Placenta"
DOI: 10.1016/j.placenta.2018.06.305
Abstract: INTRODUCTION We established an in-vitro model for the study of human fetal membrane (FM) weakening leading to pPROM. In this model, granulocyte-macrophage colony-stimulating factor (GM-CSF) is a critical intermediate for both tumor necrosis factor-α (TNF;… read more here.
Keywords: vitro model; human fetal; csf; induced weakening ... See more keywords
Steroidogenic potential of human fetal kidney at early gestational age
Sign Up to like & getrecommendations! Published in 2019 at "Steroids"
DOI: 10.1016/j.steroids.2019.05.009
Abstract: Steroidogenic potential of the human fetal kidney (hFK) at the end of first trimester is poorly investigated. Little is known about the ontogeny of steroidogenic enzymes and activities of steroidogenic pathways in the hFK at… read more here.
Keywords: steroidogenic potential; human fetal; fetal kidney; potential human ... See more keywords
Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869
Sign Up to like & getrecommendations! Published in 2018 at "Cell Discovery"
DOI: 10.1038/s41421-018-0017-2
Abstract: Zika virus (ZIKV) is a neurotrophic flavivirus that is capable of infecting humans, leading to brain abnormalities during fetal development. The ZIKV infectivity in neural target cells remains poorly understood. Here, we found that ZIKV… read more here.
Keywords: inhibitor; fetal astrocytes; human fetal; neutral sphingomyelinase ... See more keywords