Identification of human flavin-containing monooxygenase 3 substrates by a colorimetric screening assay.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2017.01.024
Abstract: Human hepatic flavin-containing monooxygenase 3 is a phase I drug-metabolizing enzyme that is responsible for the oxidation of a variety of drugs and xenobiotics. This work reports on a high throughput rapid colorimetric assay for… read more here.
Keywords: containing monooxygenase; identification human; flavin containing; assay ... See more keywords
Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114763
Abstract: Out of the five isoforms of human flavin-containing monooxygenase (hFMO), FMO1 and FMO3 are the most relevant to Phase I drug metabolism. They are involved in the oxygenation of xenobiotics including drugs and pesticides using… read more here.
Keywords: flavin containing; human flavin; containing monooxygenase; hydroperoxyflavin intermediate ... See more keywords