Articles with "human gingiva" as a keyword



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Astragaloside attenuates lipopolysaccharide‐induced cell apoptosis in human gingiva cells via MAPK signaling pathway

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28286

Abstract: The aim of this study was to research the antiapoptotic effect of astragaloside, the principal component of Astragalus membranaceus (Fisch) Bge, in human gingiva cells induced by lipopolysaccharide (LPS). read more here.

Keywords: gingiva cells; lipopolysaccharide induced; attenuates lipopolysaccharide; human gingiva ... See more keywords
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Human Gingiva-Derived Mesenchymal Stem Cells Ameliorate Streptozoticin-induced T1DM in mice via Suppression of T effector cells and Up-regulating Treg Subsets

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-14979-5

Abstract: There is yet no cure for type 1 diabetes (T1DM) so far. A significant body of evidence has demonstrated that bone marrow-derived mesenchymal stem cells (BMSCs) showed great potential in controlling T1DM. But there exists… read more here.

Keywords: derived mesenchymal; human gingiva; stem cells; induced t1dm ... See more keywords
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Ionizing Radiation Alters the Transition/Transversion Ratio in the Exome of Human Gingiva Fibroblasts

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Published in 2020 at "Health Physics"

DOI: 10.1097/hp.0000000000001251

Abstract: Supplemental digital content is available in the text. Abstract Little is known about the mutational impact of ionizing radiation (IR) exposure on a genome-wide level in mammalian tissues. Recent advancements in sequencing technology have provided… read more here.

Keywords: ionizing radiation; quality; radiation; transition transversion ... See more keywords
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Saliva-Derived Commensal and Pathogenic Biofilms in a Human Gingiva Model

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Published in 2018 at "Journal of Dental Research"

DOI: 10.1177/0022034517729998

Abstract: In vitro models that closely mimic human host-microbiome interactions can be a powerful screening tool for antimicrobials and will hold great potential for drug validation and discovery. The aim of this study was to develop… read more here.

Keywords: pathogenic biofilms; human gingiva; oral biofilms; commensal pathogenic ... See more keywords
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Stable reconstructed human gingiva–microbe interaction model: Differential response to commensals and pathogens

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Published in 2022 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2022.991128

Abstract: Background To investigate human oral health and disease, models are required which represent the interactions between the oral mucosa and microbiome. Our aim was to develop an organotypic model which maintains viability of both host… read more here.

Keywords: rhg; reconstructed human; human gingiva; model ... See more keywords
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Genome-Wide DNA Alterations in X-Irradiated Human Gingiva Fibroblasts

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21165778

Abstract: While ionizing radiation (IR) is a powerful tool in medical diagnostics, nuclear medicine, and radiology, it also is a serious threat to the integrity of genetic material. Mutagenic effects of IR to the human genome… read more here.

Keywords: gingiva fibroblasts; genome wide; human gingiva; induced dna ... See more keywords
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Permeability of Fresh and Frozen Porcine and Human Gingiva and the Effect of Storage Duration

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Published in 2023 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics15051492

Abstract: The gingiva is the target site for some topical drugs, but the permeability of human gingiva has not been systematically evaluated. Pigs are a common animal model for in vitro membrane transport studies. The objectives… read more here.

Keywords: porcine gingiva; human gingiva; gingiva; permeability ... See more keywords