Normalization in Human Glioma Tissue.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9833-3_13
Abstract: For tissues obtained from glioma samples with/without nonneoplastic brain there is no consensus for universal reference gene but there are some potential genes that might have good stability, under certain conditions. Considering all points described… read more here.
Keywords: normalization human; human glioma; glioma; tissue ... See more keywords
In Vivo Molecular Profiling of Human Glioma
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-018-0676-2
Abstract: PurposeTo assess the diagnostic performance of dynamic susceptibility contrast perfusion magnetic resonance perfusion imaging (DSC-MRI) for in vivo human glioma molecular profiling.MethodsIn this study 100 patients with histopathologically confirmed glioma who provided written informed consent were… read more here.
Keywords: human glioma; diagnostic performance; glioma; vivo ... See more keywords
Experimental and clinical studies on radiation and curcumin in human glioma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-020-03432-2
Abstract: There is progressing evidence for the anti-cancer potential of the natural compound and dietary spice curcumin. Curcumin has been ascribed to be cytotoxic for various tumour cell types, to inhibit cell proliferation and to interfere… read more here.
Keywords: studies radiation; clinical studies; human glioma; experimental clinical ... See more keywords
Design, synthesis, DNA binding studies and evaluation of anticancer potential of novel substituted biscarbazole derivatives against human glioma U87 MG cell line.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103911
Abstract: In this research paper, we report the design and synthesis of novel substituted biscarbazole derivatives which were characterized by 1H and 13C NMR, high resolution mass spectroscopy (HRMS). The SAR study of the compounds is… read more here.
Keywords: novel; cell line; human glioma; biscarbazole derivatives ... See more keywords
Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.01.030
Abstract: Background Glioma is the most common and aggressive primary brain tumor with polygenic susceptibility. The cytoplasmic/nuclear shuttling protein, SLC2A4RG (SLC2A4 regulator), has been identified in the 20q13.33 region influencing glioma susceptibility by genome-wide association studies… read more here.
Keywords: human glioma; cell; glioma; caspase caspase ... See more keywords
Construction of a Zn(II)-containing MOF for highly selective detection of picric acid and inhibition of human glioma cell growth
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.127359
Abstract: Abstract A novel Zinc-based metal-organic framework [Zn2(OH)2(H2TCPP)](DMF)3 (1) was constructed by using a novel rigid symmetric tetracarboxylic connector, 2,3,5,6-tetrakis (4-carboxyphenyl)pyrazine (H4TCPP). The cross-linkage of Zn(II)-based 1D rod secondary building units (SBUs) with the H2TCPP2− ligands… read more here.
Keywords: construction containing; human glioma; containing mof; picric acid ... See more keywords
Monacolin K Induces Apoptosis of Human Glioma U251 Cells by Triggering ROS-Mediated Oxidative Damage and Regulating MAPKs and NF-κB Pathways.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.3c00104
Abstract: Monacolin K (MK), a polyketo secondary metabolic compound of the mold genus Monascus, can promote the apoptosis of malignant cancer cells, possessing potential antitumor properties. However, its mechanism of action on gliomas remains unclear. Here,… read more here.
Keywords: cells triggering; human glioma; u251 cells; triggering ros ... See more keywords
Selective Toxicity Effect of Fatty Acids Omega-3, 6 and 9 Combination on Glioblastoma Neurons through their Mitochondria.
Sign Up to like & getrecommendations! Published in 2021 at "Drug research"
DOI: 10.1055/a-1640-8561
Abstract: Glioblastoma (GBM) is one of the most common malignant tumors of the central nervous system that occurs in the brain and is a deadly disease. Despite the different approaches to the treatment of this malignancy,… read more here.
Keywords: combination; human glioma; toxicity; mitochondria isolated ... See more keywords
Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2114456119
Abstract: Significance Cancer immunotherapies, including checkpoint inhibitor blocking antibodies and antibody drug conjugates, currently revolutionize cancer treatment. However, a remaining challenge is the identification of tumor surfaceome (TS) targets for the design of more rational, individualized… read more here.
Keywords: endocytome human; glioma divergent; divergent depends; landscape surfaceome ... See more keywords
FOXM1‐mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Neuropathology"
DOI: 10.1111/neup.12824
Abstract: Glioma is the most common malignant tumor in the central nervous system and has a high mortality rate. Temozolomide (TMZ) is a widely used chemotherapeutic drug for glioma. NDC80 kinetochore complex (NUF2) is suggested to… read more here.
Keywords: cells regulating; tmz resistant; glioma cells; human glioma ... See more keywords
Long non-coding RNA LINC00525 regulates the proliferation and epithelial to mesenchymal transition of human glioma cells by sponging miR-338-3p
Sign Up to like & getrecommendations! Published in 2020 at "AMB Express"
DOI: 10.1186/s13568-020-01094-4
Abstract: Long non-coding RNA (LncRNA) LINC00525 has been shown to be upregulated in several human cancers and deduced to possess caner regulatory role. The regulation of molecular mechanics of human glioma by lncRNA-LINC00525 through microRNA sponging… read more here.
Keywords: lncrna linc00525; glioma cells; human glioma; glioma ... See more keywords