Comparative Molecular Life History of Spontaneous Canine and Human Gliomas.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.01.004
Abstract: Sporadic gliomas in companion dogs provide a window on the interaction between tumorigenic mechanisms and host environment. We compared the molecular profiles of canine gliomas with those of human pediatric and adult gliomas to characterize… read more here.
Keywords: comparative molecular; canine gliomas; gliomas; canine ... See more keywords
TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas
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DOI: 10.1158/1078-0432.ccr-21-0312
Abstract: Purpose: The epigenetic mechanisms involved in transcriptional regulation leading to malignant phenotype in gliomas remains poorly understood. Topoisomerase IIB (TOP2B), an enzyme that decoils and releases torsional forces in DNA, is overexpressed in a subset… read more here.
Keywords: human gliomas; oncogenes human; glioma; multiple oncogenes ... See more keywords
The Significance of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Human Gliomas
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DOI: 10.3390/ijms19092724
Abstract: Neuron glial antigen 2 (NG2) is a chondroitin sulphate proteoglycan 4 (CSPG4) that occurs in developing and adult central nervous systems (CNSs) as a marker of oligodendrocyte precursor cells (OPCs) together with platelet-derived growth factor… read more here.
Keywords: chondroitin; cspg4; proteoglycan cspg4; human gliomas ... See more keywords