Uncovering a multitude of human glucocorticoid receptor variants: an expansive survey of a single gene
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genetics"
DOI: 10.1186/s12863-019-0718-z
Abstract: Background Glucocorticoids are commonly used in the clinical setting for their potent anti-inflammatory effects; however, significant variations in response to treatment have been demonstrated. Although the underlying mechanisms have yet to be fully understood, this… read more here.
Keywords: human glucocorticoid; uncovering multitude; gene; hgr ... See more keywords
The human Glucocorticoid Receptor beta: From Molecular Mechanisms to Clinical Implications.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac150
Abstract: Glucocorticoids play a fundamental role in a plethora of cellular processes and physiologic functions through binding on a ubiquitously expressed receptor, the glucocorticoid receptor (GR) that functions as a ligand-activated transcription factor influencing the transcription… read more here.
Keywords: glucocorticoid receptor; beta molecular; human glucocorticoid; receptor ... See more keywords