Human haematopoietic stem cell lineage commitment is a continuous process
Sign Up to like & getrecommendations! Published in 2017 at "Nature cell biology"
DOI: 10.1038/ncb3493
Abstract: Blood formation is believed to occur through stepwise progression of haematopoietic stem cells (HSCs) following a tree-like hierarchy of oligo-, bi- and unipotent progenitors. However, this model is based on the analysis of predefined flow-sorted… read more here.
Keywords: lineage commitment; cell; haematopoietic stem; human haematopoietic ... See more keywords
Mapping human haematopoietic stem cells from haemogenic endothelium to birth.
Sign Up to like & getrecommendations! Published in 2022 at "Nature"
DOI: 10.1038/s41586-022-04571-x
Abstract: The ontogeny of human haematopoietic stem cells (HSCs) is poorly defined owing to the inability to identify HSCs as they emerge and mature at different haematopoietic sites1. Here we created a single-cell transcriptome map of… read more here.
Keywords: birth; hsc; stem cells; human haematopoietic ... See more keywords