Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89451-6
Abstract: Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM). We analyzed the transcriptome… read more here.
Keywords: phenotype; mutant mice; hcm; human hcm ... See more keywords
Feline Hypertrophic Cardiomyopathy: A Spontaneous Large Animal Model of Human HCM
Sign Up to like & getrecommendations! Published in 2017 at "Cardiology Research"
DOI: 10.14740/cr578w
Abstract: Hypertrophic cardiomyopathy (HCM) is a common disease in pet cats, affecting 10-15% of the pet cat population. The similarity to human HCM, the rapid progression of disease, and the defined and readily determined endpoints of… read more here.
Keywords: hypertrophic cardiomyopathy; hcm; model; human hcm ... See more keywords