Altered cyclic nucleotide-binding and pore opening in a diseased human HCN4 channel.
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DOI: 10.1016/j.bpj.2022.02.035
Abstract: A growing number of nonsynonymous mutations in the human HCN4 channel gene, the major component of the funny channel of the sinoatrial node, are associated with disease but how they impact channel structure and function,… read more here.
Keywords: channel; nucleotide binding; cyclic nucleotide; human hcn4 ... See more keywords