Exosomes derived from chemically induced human hepatic progenitors inhibit oxidative stress induced cell death
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27447
Abstract: Abstract The emerging field of regenerative medicine has revealed that the exosome contributes to many aspects of development and disease through intercellular communication between donor and recipient cells. However, the biological functions of exosomes secreted… read more here.
Keywords: derived chemically; exosomes derived; human hepatic; cell death ... See more keywords
Characterization of a peptide containing the major heparin binding domain of human hepatic lipase
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Peptide Science"
DOI: 10.1002/psc.3123
Abstract: Human hepatic lipase (hHL) is a cell surface associated enzyme that hydrolyzes triacylglycerols and phospholipids within circulating lipoproteins. We hypothesized that an amino acid sequence mimicking the major heparin binding domain (HBD) of hHL will… read more here.
Keywords: heparin; peptide; hhl; human hepatic ... See more keywords
Differential impacts of individual and combined exposures of deoxynivalenol and zearalenone on the HepaRG human hepatic cell proteome.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2017.11.025
Abstract: Numerous surveys have highlighted the natural co-occurrence of deoxynivalenol (DON) and zearalenone (ZEA) mycotoxins in food and feed. Nevertheless, data regarding cellular mechanisms involved in response to their individual and simultaneous exposures are lacking. In… read more here.
Keywords: response; exposure; mycotoxin; human hepatic ... See more keywords
Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokinetics
Sign Up to like & getrecommendations! Published in 2019 at "Xenobiotica"
DOI: 10.1080/00498254.2019.1629043
Abstract: Abstract 1. Organic anion transporting polypeptides (OATPs) belong to the superfamily of solute carriers (SLC), which are important membrane transporters in animals and humans. Liver is an important organ for drug disposition. In human liver,… read more here.
Keywords: genetic polymorphisms; drug; effect; human hepatic ... See more keywords
Exploiting three-dimensional human hepatic constructs to investigate the impact of rs174537 on fatty acid metabolism
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262173
Abstract: The Modern Western Diet has been associated with the rise in metabolic and inflammatory diseases, including obesity, diabetes, and cardiovascular disease. This has been attributed, in part, to the increase in dietary omega-6 polyunsaturated fatty… read more here.
Keywords: three dimensional; exploiting three; rs174537; fatty acid ... See more keywords
Cytotoxicity of Human Hepatic Intrasinusoidal Gamma/Delta T Cells Depends on Phospho-antigen and NK Receptor Signaling
Sign Up to like & getrecommendations! Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.16135
Abstract: Background/Aim: We previously showed that human hepatic intrasinusoidal (HI) natural killer (NK) T cells selectively eliminate hepatocellular carcinoma (HCC) cell lines. In this study, we investigated the underlying mechanisms on how HI γδ T cells,… read more here.
Keywords: cytotoxicity; phospho antigen; hepatic intrasinusoidal; cytotoxicity cells ... See more keywords
The First Case of Human Hepatic Fasciolosis Presented as Hepatic Pseudotumor Histopathologically Diagnosed in Romania—A Case Report
Sign Up to like & getrecommendations! Published in 2023 at "Healthcare"
DOI: 10.3390/healthcare11101451
Abstract: Human hepatic fasciolosis has been reported in 81 countries, some of which are endemic areas. In Europe, case reports from humans were published in Portugal, Spain, France, and Italy. Regarding Romania, we do not have… read more here.
Keywords: hepatic fasciolosis; diagnosed romania; fasciolosis; human hepatic ... See more keywords
Evaluation of the Effects of Microgravity on Activated Primary Human Hepatic Stellate Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137429
Abstract: In recent years, research has been conducted to develop new medical treatments by simulating environments existing in space, such as zero-gravity. In this study, we evaluated the cell proliferation and gene expression of activated primary… read more here.
Keywords: stellate cells; primary human; proliferation; activated primary ... See more keywords
Hempseed (Cannabis sativa) Peptide H3 (IGFLIIWV) Exerts Cholesterol-Lowering Effects in Human Hepatic Cell Line
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14091804
Abstract: Hempseed (Cannabis sativa) protein is an important source of bioactive peptides. H3 (IGFLIIWV), a transepithelial transported intestinal peptide obtained from the hydrolysis of hempseed protein with pepsin, carries out antioxidant and anti-inflammatory activities in HepG2… read more here.
Keywords: cannabis sativa; hempseed cannabis; human hepatic; peptide ... See more keywords