An integrative view of human hippocampal function: Differences with other species and capacity considerations
Sign Up to like & getrecommendations! Published in 2023 at "Hippocampus"
DOI: 10.1002/hipo.23527
Abstract: We describe an integrative model that encodes associations between related concepts in the human hippocampal formation, constituting the skeleton of episodic memories. The model, based on partially overlapping assemblies of “concept cells,” contrast markedly with… read more here.
Keywords: capacity; human hippocampal; overlapping assemblies; integrative view ... See more keywords
Adult Human Hippocampal Neurogenesis: Controversy and Evidence.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2018.04.002
Abstract: The hippocampus has been described as one of the few sites in the mammalian brain capable of generating new cells continuously throughout life. Two recent studies that report contradicting findings on adult human hippocampal neurogenesis,… read more here.
Keywords: adult human; hippocampal neurogenesis; human hippocampal; neurogenesis controversy ... See more keywords
The Curious Case of Human Hippocampal Neurogenesis.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00063
Abstract: Neurogenesis in the human brain has been validated to occur throughout adulthood. Recently, the human hippocampal neurogenesis field has been shaken by two significant reports that have been published with opposite reports, and these path-breaking… read more here.
Keywords: neurogenesis; hippocampal neurogenesis; human hippocampal; curious case ... See more keywords
Lithium treatment and human hippocampal neurogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01695-y
Abstract: Lithium is a first-line treatment for bipolar disorder, where it acts as a mood-stabilizing agent. Although its precise mechanism remains unclear, neuroimaging studies have shown that lithium accumulates in the hippocampus and that chronic use… read more here.
Keywords: neurogenesis; treatment human; lithium treatment; human hippocampal ... See more keywords
HippoMaps: multiscale cartography of human hippocampal organization
Sign Up to like & getrecommendations! Published in 2024 at "Nature Methods"
DOI: 10.1038/s41592-025-02783-3
Abstract: The hippocampus has a unique microarchitecture, is situated at the nexus of multiple macroscale functional networks, contributes to numerous cognitive as well as affective processes, and is highly susceptible to brain pathology across common disorders.… read more here.
Keywords: multiscale cartography; human hippocampal; hippocampal organization; cartography human ... See more keywords
The Effective Connectivity of the Human Hippocampal Memory System.
Sign Up to like & getrecommendations! Published in 2022 at "Cerebral cortex"
DOI: 10.1093/cercor/bhab442
Abstract: Effective connectivity measurements in the human hippocampal memory system based on the resting-state blood oxygenation-level dependent signal were made in 172 participants in the Human Connectome Project to reveal the directionality and strength of the… read more here.
Keywords: connectivity; memory system; effective connectivity; hippocampal memory ... See more keywords
Serum from Older Adults Increases Apoptosis and Molecular Aging Markers in Human Hippocampal Progenitor Cells
Sign Up to like & getrecommendations! Published in 2021 at "Aging and Disease"
DOI: 10.14336/ad.2021.0409
Abstract: Age-related alteration in neural stem cell function is linked to neurodegenerative conditions and cognitive decline. In rodents, this can be reversed by exposure to a young systemic milieu and conversely, the old milieu can inhibit… read more here.
Keywords: serum; serum older; hippocampal progenitor; cell ... See more keywords
Caffeine Compromises Proliferation of Human Hippocampal Progenitor Cells
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00806
Abstract: The age-associated reduction in the proliferation of neural stem cells (NSCs) has been associated with cognitive decline. Numerous factors have been shown to modulate this process, including dietary components. Frequent consumption of caffeine has been… read more here.
Keywords: caffeine; proliferation; positive cells; human hippocampal ... See more keywords
Age-Related sncRNAs in Human Hippocampal Tissue Samples: Focusing on Deregulated miRNAs
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252312872
Abstract: Small non-coding RNAs (sncRNAs), particularly microRNAs (miRNAs), play an important role in transcriptome regulation by binding to mRNAs and post-transcriptionally inhibiting protein production. This regulation occurs in both physiological and pathological conditions, where the expression… read more here.
Keywords: related sncrnas; human hippocampal; hsa mir; age related ... See more keywords
A map of abstract relational knowledge in the human hippocampal–entorhinal cortex
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.17086
Abstract: The hippocampal–entorhinal system encodes a map of space that guides spatial navigation. Goal-directed behaviour outside of spatial navigation similarly requires a representation of abstract forms of relational knowledge. This information relies on the same neural… read more here.
Keywords: knowledge; hippocampal entorhinal; human hippocampal; map abstract ... See more keywords