Aerobic exercise, cardiorespiratory fitness, and the human hippocampus
Sign Up to like & getrecommendations! Published in 2021 at "Hippocampus"
DOI: 10.1002/hipo.23337
Abstract: The hippocampus is particularly susceptible to neurodegeneration. Physical activity, specifically increasing cardiorespiratory fitness via aerobic exercise, shows promise as a potential method for mitigating hippocampal decline in humans. Numerous studies have now investigated associations between… read more here.
Keywords: hippocampus; human hippocampus; cardiorespiratory fitness; exercise ... See more keywords
Properties and hemispheric differences of theta oscillations in the human hippocampus
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23412
Abstract: The left and right primate hippocampi (LH and RH) are thought to support distinct functions, but little is known about differences between the hemispheres at the neuronal level. We recorded single‐neuron and local field potentials… read more here.
Keywords: properties hemispheric; human hippocampus; hippocampus; hippocampus properties ... See more keywords
Imaging the human hippocampus with optically-pumped magnetoencephalography
Sign Up to like & getrecommendations! Published in 2019 at "Neuroimage"
DOI: 10.1016/j.neuroimage.2019.116192
Abstract: Optically-pumped (OP) magnetometers allow magnetoencephalography (MEG) to be performed while a participant’s head is unconstrained. To fully leverage this new technology, and in particular its capacity for mobility, the activity of deep brain structures which… read more here.
Keywords: hippocampus; human hippocampus; imaging human; hippocampus optically ... See more keywords
On pattern separation in the primate, including human, hippocampus
Sign Up to like & getrecommendations! Published in 2021 at "Trends in Cognitive Sciences"
DOI: 10.1016/j.tics.2021.07.004
Abstract: In a recent article, Quiroga argued that pattern separation may not occur in the human hippocampus [1]. This argument was based on neuronal recordings in the human hippocampus that showed that many neurons respond to… read more here.
Keywords: pattern separation; human hippocampus; separation; separation primate ... See more keywords
A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14518-3
Abstract: The functional organization of the hippocampus is distributed as a gradient along its longitudinal axis that explains its differential interaction with diverse brain systems. We show that the location of human tissue samples extracted along… read more here.
Keywords: hippocampus; human hippocampus; gradient; longitudinal axis ... See more keywords
Beta-band power modulation in the human hippocampus during a reaching task.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/ab937f
Abstract: Objective Characterize the role of the beta-band (13-30 Hz) in the human hippocampus during the execution of voluntary movement. Approach We recorded electrophysiological activity in human hippocampus during a reach task using stereotactic electroencephalography (SEEG).… read more here.
Keywords: human hippocampus; beta band; hippocampus; power ... See more keywords
Sparse Large-Scale Nonlinear Dynamical Modeling of Human Hippocampus for Memory Prostheses
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Neural Systems and Rehabilitation Engineering"
DOI: 10.1109/tnsre.2016.2604423
Abstract: In order to build hippocampal prostheses for restoring memory functions, we build sparse multi-input, multi-output (MIMO) nonlinear dynamical models of the human hippocampus. Spike trains are recorded from hippocampal CA3 and CA1 regions of epileptic… read more here.
Keywords: memory; spike trains; human hippocampus; memory prostheses ... See more keywords
Loss of lamin‐B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus
Sign Up to like & getrecommendations! Published in 2021 at "Aging Cell"
DOI: 10.1111/acel.13521
Abstract: The increase in senescent cells in tissues, including the brain, is a general feature of normal aging and age‐related pathologies. Senescent cells exhibit a specific phenotype, which includes an altered nuclear morphology and transcriptomic changes.… read more here.
Keywords: lamin; senescence vitro; nuclear morphology; senescence ... See more keywords
Identification of exon skipping events associated with Alzheimer’s disease in the human hippocampus
Sign Up to like & getrecommendations! Published in 2018 at "BMC Medical Genomics"
DOI: 10.1186/s12920-018-0453-8
Abstract: BackgroundAt least 90% of human genes are alternatively spliced. Alternative splicing has an important function regulating gene expression and miss-splicing can contribute to risk for human diseases, including Alzheimer’s disease (AD).MethodsWe developed a splicing decision… read more here.
Keywords: human hippocampus; skipping events; alzheimer disease; exon skipping ... See more keywords
Layer-Specific Vesicular Glutamate Transporter 1 Immunofluorescence Levels Delineate All Layers of the Human Hippocampus Including the Stratum lucidum
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.789903
Abstract: The hippocampal formation consists of the Ammon’s horn (cornu Ammonis with its regions CA1-4), dentate gyrus, subiculum, and the entorhinal cortex. The rough extension of the regions CA1-3 is typically defined based on the density… read more here.
Keywords: vesicular glutamate; hippocampus; stratum lucidum; glutamate transporter ... See more keywords