Production of a Human Histamine Receptor for NMR Spectroscopy in Aqueous Solutions
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DOI: 10.3390/biom11050632
Abstract: G protein-coupled receptors (GPCRs) bind a broad array of extracellular molecules and transmit intracellular signals that initiate physiological responses. The signal transduction functions of GPCRs are inherently related to their structural plasticity, which can be… read more here.
Keywords: production; human histamine; nmr spectroscopy; spectroscopy ... See more keywords
Ergotamine Stimulates Human 5-HT4-Serotonin Receptors and Human H2-Histamine Receptors in the Heart
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DOI: 10.3390/ijms24054749
Abstract: Ergotamine (2′-methyl-5′α-benzyl-12′-hydroxy-3′,6′,18-trioxoergotaman) is a tryptamine-related alkaloid from the fungus Claviceps purpurea. Ergotamine is used to treat migraine. Ergotamine can bind to and activate several types of 5-HT1-serotonin receptors. Based on the structural formula of ergotamine,… read more here.
Keywords: ht4 serotonin; histamine receptors; receptors human; serotonin receptors ... See more keywords