Supramolecular Nanofibers Block SARS-CoV-2 Entry into Human Host Cells
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.3c02447
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection relies on its spike protein binding to angiotensin-converting enzyme 2 (ACE2) on host cells to initiate cellular entry. Blocking the interactions between the spike protein and… read more here.
Keywords: host cells; entry; supramolecular nanofibers; human host ... See more keywords
Identification of Human Host Substrates of the SARS-CoV-2 Mpro and PLpro Using Subtiligase N-Terminomics
Sign Up to like & getrecommendations! Published in 2023 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.2c00458
Abstract: The recent emergence of SARS-CoV-2 in the human population has caused a global pandemic. The virus encodes two proteases, Mpro and PLpro, that are thought to play key roles in the suppression of host protein… read more here.
Keywords: mpro plpro; cov mpro; substrates sars; human host ... See more keywords
The ß-ketoadipate pathway of Acinetobacter baumannii is involved in complement resistance and affects resistance against aromatic antibiotics.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental microbiology reports"
DOI: 10.1111/1758-2229.13042
Abstract: Acinetobacter baumannii can thrive on a broad range of substrates such as sugars, alcohols, lipids, amino acids and aromatic compounds. The latter three are abundant in the human host and are potential candidates as carbon… read more here.
Keywords: complement resistance; ketoadipate pathway; acinetobacter baumannii; human host ... See more keywords
Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-inflammatory Environment in the Human Host
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.03125-22
Abstract: Interactions between the host and bacteria at sites of infection in humans are poorly understood. We inoculated human volunteers on the upper arm with the skin pathogen H. ducreyi or a buffer control and biopsied… read more here.
Keywords: environment; anti inflammatory; pro anti; ducreyi ... See more keywords
A zooprophylaxis strategy using l-lactic acid (Abate) to divert host-seeking malaria vectors from human host to treated non-host animals
Sign Up to like & getrecommendations! Published in 2020 at "Malaria Journal"
DOI: 10.1186/s12936-020-3136-9
Abstract: Zooprophylaxis is a technique in which blood-seeking vectors are diverted to non-host animals in order to lower blood-feeding rates on human hosts. The success of this technique depends on the host preference of the vector… read more here.
Keywords: host animals; host; human host; non host ... See more keywords
RNA editing increases the nucleotide diversity of SARS-CoV-2 in human host cells.
Sign Up to like & getrecommendations! Published in 2022 at "PLoS genetics"
DOI: 10.1371/journal.pgen.1010130
Abstract: SARS-CoV-2 is a positive-sense, single-stranded RNA virus responsible for the COVID-19 pandemic. It remains unclear whether and to what extent the virus in human host cells undergoes RNA editing, a major RNA modification mechanism. Here… read more here.
Keywords: rna editing; editing increases; sars cov; human host ... See more keywords
The human host response to monkeypox infection: a proteomic case series study
Sign Up to like & getrecommendations! Published in 2022 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202216643
Abstract: The rapid rise of monkeypox (MPX) cases outside previously endemic areas prompts for a better understanding of the disease. We studied the plasma proteome of a group of MPX patients with a similar infection history… read more here.
Keywords: case series; human host; host response; response ... See more keywords