Immunohistochemistry of Human Hsp60 in Health and Disease: From Autoimmunity to Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7477-1_21
Abstract: Hsp60 (also called Cpn60) is a chaperonin with essential functions for cell physiology and survival. Additionally, its involvement in the pathogenesis of a variety of diseases (e.g., some autoimmune disorders and cancer) is becoming evident… read more here.
Keywords: immunohistochemistry human; human hsp60; disease autoimmunity; health disease ... See more keywords
Inhibition of Aβ1-42 fibrillation by chaperonins: human Hsp60 is a stronger inhibitor than its bacterial homologue GroEL.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00183
Abstract: Alzheimer's disease is a chronic neurodegenerative disease characterized by the accumulation of pathological aggregates of amyloid beta peptide. Many efforts have been focused on understanding peptide aggregation pathways and on identification of molecules able to… read more here.
Keywords: aggregation; human hsp60; groel; fibrillation chaperonins ... See more keywords