Unbiased RACE-Based Massive Parallel Surveys of Human IgA Antibody Repertoires.
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DOI: 10.1007/978-1-4939-7180-0_5
Abstract: For investigations of human B-cell receptor (BCR) repertoires, we have developed a protocol for large-scale surveys of human antibody heavy chain (VH) rearrangements. Here we study IgA repertoires, as more IgA antibodies are synthesized in… read more here.
Keywords: race based; unbiased race; human iga; antibody ... See more keywords
Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo
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DOI: 10.1080/19420862.2018.1433974
Abstract: ABSTRACT Respiratory syncytial virus (RSV) infection is a leading cause of hospitalization and mortality in young children. Protective therapy options are limited. Currently, palivizumab, a monoclonal IgG1 antibody, is the only licensed drug for RSV… read more here.
Keywords: iga; human iga; infection; palivizumab motavizumab ... See more keywords
Microbial ecology perturbation in human IgA deficiency
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DOI: 10.1126/scitranslmed.aan1217
Abstract: IgA influences bacterial fitness in the intestinal lumen and is only partially compensated for by IgM in selective IgA-deficient patients. IgA leads the way in the gut IgA is the most abundant mucosal antibody, and… read more here.
Keywords: iga; human iga; iga deficiency; ecology ... See more keywords