Epitope delimitation: A new method for defining epitopes of human IgG‐reactive antigenic peptides based on rabbit‐recognized epitope motifs
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.29388
Abstract: The use of precise epitope peptides as antigens is essential for accurate serological diagnosis of viral‐infected individuals, but now it remains an unsolvable problem for mapping precise B cell epitopes (BCEs) recognized by human serum.… read more here.
Keywords: human igg; epitope delimitation; igg reactive; rabbit ... See more keywords
A novel mouse strain optimized for chronic human antibody administration
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123002119
Abstract: Significance Species differences in IgG Fc–Fcγ receptor (FcγR) interactions have made humanized mouse models an attractive strategy to evaluate the efficacy and toxicity of human antibodies. We previously published a humanized FcγR mouse model that… read more here.
Keywords: human igg; administration; mouse strain; mouse ... See more keywords
Characterization of the interactions of rabbit neonatal Fc receptor (FcRn) with rabbit and human IgG isotypes
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DOI: 10.1371/journal.pone.0185662
Abstract: Despite the increasing importance of rabbit as an animal model in pharmacological studies like investigating placental transfer of therapeutic IgGs, little is known about the molecular interaction of the rabbit neonatal Fc receptor (FcRn) with… read more here.
Keywords: human igg; fcrn rabbit; rabbit human; igg isotypes ... See more keywords
Detection of Biomarker Clusterin in SERS Immunoassays on Al Foil After Substrate Selection and Assay Optimization with Fluorescently Labeled Antibodies
Sign Up to like & getrecommendations! Published in 2025 at "Molecules"
DOI: 10.3390/molecules30193974
Abstract: Clusterin plays an important role in carcinogenesis and serves as an important diagnostic biomarker of various clinical conditions. This work describes an application of a surface-enhanced Raman scattering (SERS)-based immunoassay using Al foil substrate that… read more here.
Keywords: detection; foil substrate; clusterin; human igg ... See more keywords