Structural analysis of the complex between influenza B nucleoprotein and human importin-α
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DOI: 10.1038/s41598-017-17458-z
Abstract: Influenza viruses are negative strand RNA viruses that replicate in the nucleus of the cell. The viral nucleoprotein (NP) is the major component of the viral ribonucleoprotein. In this paper we show that the NP… read more here.
Keywords: human importin; analysis complex; importin; influenza ... See more keywords
Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution
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DOI: 10.1038/s41598-021-03729-3
Abstract: Shuttling of macromolecules between nucleus and cytoplasm is a tightly regulated process mediated through specific interactions between cargo and nuclear transport proteins. In the classical nuclear import pathway, importin alpha recognizes cargo exhibiting a nuclear… read more here.
Keywords: importin alpha; importin; alpha isoforms; cargo free ... See more keywords