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Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.07.017
Abstract: Human indoleamine 2,3-dioxygenase 1 (IDO) is a heme enzyme that catalyzes the first reaction of the main metabolic pathway of L-tryptophan (Trp) to produce N-formylkynurenin. The reaction involves cleavage of the C2=C3 bond in the…
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Keywords:
human indoleamine;
trp;
reaction;
indoleamine dioxygenase ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22105102
Abstract: Genetic engineering of plants has turned out to be an attractive approach to produce various secondary metabolites. Here, we attempted to produce kynurenine, a health-promoting metabolite, in plants of Nicotiana tabacum (tobacco) transformed by Agrobacterium…
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Keywords:
ido1;
human indoleamine;
production;
indoleamine dioxygenase ... See more keywords