Large‐Scale Production of Wholly Cellular Bioinks via the Optimization of Human Induced Pluripotent Stem Cell Aggregate Culture in Automated Bioreactors
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201138
Abstract: Combining the sustainable culture of billions of human cells and the bioprinting of wholly cellular bioinks offers a pathway toward organ‐scale tissue engineering. Traditional 2D culture methods are not inherently scalable due to cost, space,… read more here.
Keywords: culture; cell; induced pluripotent; wholly cellular ... See more keywords
Cellular Alignment and Matrix Stiffening Induced Changes in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402228
Abstract: Biological processes are inherently dynamic, necessitating biomaterial platforms capable of spatiotemporal control over cellular organization and matrix stiffness for accurate study of tissue development, wound healing, and disease. However, most in vitro platforms remain static.… read more here.
Keywords: matrix; pluripotent stem; cell; human induced ... See more keywords
Micropatterned substrates with physiological stiffness promote cell maturation and Pompe disease phenotype in human induced pluripotent stem cell‐derived skeletal myocytes
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27075
Abstract: Recent advances in bioengineering have enabled cell culture systems that more closely mimic the native cellular environment. Here, we demonstrated that human induced pluripotent stem cell (iPSC)‐derived myogenic progenitors formed highly‐aligned myotubes and contracted when… read more here.
Keywords: human induced; disease; stem cell; pluripotent stem ... See more keywords
Quantitative Assessment of Sialo‐Glycoproteins and N‐Glycans during Cardiomyogenic Differentiation of Human Induced Pluripotent Stem Cells
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700100
Abstract: Human induced pluripotent stem‐cell‐derived cardiomyocytes (hiPSC CMs) may be used in regenerative medicine for individualized tissue transplants in the future. For application in patients, the generated CMs have to be highly pure and well characterized.… read more here.
Keywords: glycoproteins glycans; sialo glycoproteins; human induced; differentiation ... See more keywords
What doesn't kill you makes you (and your descendants) stronger: a perspective on early‐life exposure to human‐induced challenges as a trigger of compensatory mechanisms
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Avian Biology"
DOI: 10.1002/jav.03418
Abstract: Although the negative impact of human‐induced environmental effects on bird populations has been widely demonstrated, the question of whether adaptive strategies may potentially arise as a result of unforeseen challenges is still unclear. Despite their… read more here.
Keywords: biology; compensatory mechanisms; human induced; kill makes ... See more keywords
Hypoxia and TNF‐alpha modulate extracellular vesicle release from human induced pluripotent stem cell‐derived cardiomyocytes
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70000
Abstract: Extracellular vesicles (EVs) have emerged as important mediators of intercellular communication in the heart under homeostatic and pathological conditions, such as myocardial infarction (MI). However, the basic mechanisms driving cardiomyocyte-derived EV (CM-EV) production following stress… read more here.
Keywords: derived cardiomyocytes; stem cell; pluripotent stem; human induced ... See more keywords
Decellularized human liver extracellular matrix (hDLM)‐mediated hepatic differentiation of human induced pluripotent stem cells (hIPSCs)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2627
Abstract: Liver tissue engineering has emerged as a promising approach in organ transplantation but has been hampered by the lack of a reliable and readily available cell source. Human induced pluripotent stem cells hiPSCs have been… read more here.
Keywords: hdlm; human induced; extracellular matrix; differentiation ... See more keywords
Generation of Quiescent Cardiac Fibroblasts Derived from Human Induced Pluripotent Stem Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/7651_2020_300
Abstract: Myocardial fibrosis is a hallmark of cardiac remodeling, which can progressively lead to heart failure, a leading cause of death worldwide. The effector cells of fibrosis in the heart are cardiac fibroblasts (CFs). There is… read more here.
Keywords: quiescent; human induced; pluripotent stem; cardiac fibroblasts ... See more keywords
Generation of Human Induced Pluripotent Stem Cells from Renal Epithelial Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_419
Abstract: In the past decades, human induced pluripotent stem cells (iPSCs) have been generated by the ectopic expression of "Yamanaka factors" in multiple somatic cells. However, the procedure to get access to donor cells is hard… read more here.
Keywords: human induced; pluripotent stem; induced pluripotent; stem ... See more keywords
Integrating Human-Induced Pluripotent Stem Cell Expansion Capability and Cardiomyocyte Differentiation Potential in a Microcarrier Suspension Culture.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_423
Abstract: Human-induced pluripotent stem cells are known for their high proliferation capacity as well as their ability to differentiate to different lineages (Ban et al., Theranostics 7(7):2067-2077, 2017; Chen et al., Stem Cell Res 15(2):365-375, 2015;… read more here.
Keywords: human induced; stem cell; differentiation; induced pluripotent ... See more keywords
Chronic Optogenetic Pacing of Human-Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0830-2_10
Abstract: The delivery of cells into damaged myocardium induces limited cardiac regeneration due to extensive cell death. In an effort to limit cell death, our lab formulates three-dimensional matrices as a delivery system for cell therapy.… read more here.
Keywords: human induced; engineered cardiac; cardiac tissues; pluripotent stem ... See more keywords