Defined serum-free culture of human infant small intestinal organoids with predetermined doses of Wnt3a and R-spondin1 from surgical specimens
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Surgery International"
DOI: 10.1007/s00383-021-04957-4
Abstract: Refinement of organoid technology is important for studying physiology and disease of the intestine. We aimed to optimize defined serum-free conditions for human infant small intestinal (SI) organoid culture with predetermined doses of Wnt3a and… read more here.
Keywords: infant small; defined serum; human infant; doses wnt3a ... See more keywords
Experimental Modeling of Necrotizing Enterocolitis in Human Infant Intestinal Enteroids
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DOI: 10.1080/08941939.2020.1829755
Abstract: Abstract Background: Experimental model systems are of paramount importance in advancing our understanding of human disease. Methods There are several limitations when using a single cell culture to recapitulate the findings in a complex organism… read more here.
Keywords: modeling necrotizing; experimental modeling; enterocolitis human; necrotizing enterocolitis ... See more keywords
Inhibition of Influenza A Virus by Human Infant Saliva
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DOI: 10.3390/v11080766
Abstract: Innate antiviral factors in saliva play a role in protection against respiratory infections. We tested the anti-influenza virus activities of saliva samples taken from human infants, 1–12 months old, with no history of prior exposure… read more here.
Keywords: human infant; influenza virus; saliva; infant saliva ... See more keywords