Development and pre-clinical evaluation in the swine model of a mucosal vaccine tablet for human influenza viruses: A proof-of-concept study.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.01.021
Abstract: Liquid vaccine formulations present some disadvantages such as stability problems, cold chain requirement or administration by trained personnel. Vaccine formulated as tablets would present a wide range of progress such as an increase stability that… read more here.
Keywords: human influenza; influenza viruses; swine model; influenza ... See more keywords
Computational analysis of drug like candidates against Neuraminidase of Human Influenza A virus subtypes
Sign Up to like & getrecommendations! Published in 2020 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2019.100284
Abstract: Abstract Influenza virus is an enveloped virus having segmented genome, coded by eight (negative-sense) RNA segments. The RNA segments are packed in a nucleocapsid protein. Neuraminidase (NA), an exosialidase, is the major antigen as well… read more here.
Keywords: human influenza; virus subtypes; influenza virus; virus ... See more keywords
Biochemical characterization of avian influenza viral polymerase containing PA or PB2 subunit from human influenza A virus.
Sign Up to like & getrecommendations! Published in 2018 at "Microbes and infection"
DOI: 10.1016/j.micinf.2018.04.003
Abstract: Adaptive mutations in viral polymerase, which is composed of PB1, PB2, and PA, of avian influenza viruses are major genetic determinants of the host range. In this study, to elucidate the molecular mechanism of mammalian… read more here.
Keywords: human influenza; avian influenza; wsn; polymerase ... See more keywords
Human Influenza Epidemiology.
Sign Up to like & getrecommendations! Published in 2020 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a038356
Abstract: Influenza virus infections are common in people of all ages. Epidemics occur in the winter months in temperate locations and at varying times of the year in subtropical and tropical locations. Most influenza virus infections… read more here.
Keywords: human influenza; influenza; virus infections; influenza epidemiology ... See more keywords
Naturally occurring mutations in PB1 affect influenza A virus replication fidelity, virulence, and adaptability
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-019-0547-4
Abstract: BackgroundMutations in the PB1 subunit of RNA-dependent RNA polymerase (RdRp) of influenza A virus can affect replication fidelity. Before the influenza A/H1N1 pandemic in 2009, most human influenza A/H1N1 viruses contained the avian-associated residue, serine,… read more here.
Keywords: human influenza; fidelity; pb1 216g; influenza ... See more keywords
Continental synchronicity of human influenza virus epidemics despite climactic variation
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006780
Abstract: The factors that determine the pattern and rate of spread of influenza virus at a continental-scale are uncertain. Although recent work suggests that influenza epidemics in the United States exhibit a strong geographical correlation, the… read more here.
Keywords: human influenza; continental synchronicity; synchronicity human; influenza virus ... See more keywords
New Diagnostic Assays for Differential Diagnosis Between the Two Distinct Lineages of Bovine Influenza D Viruses and Human Influenza C Viruses
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2020.605704
Abstract: Influenza D virus (IDV), a novel orthomyxovirus, is currently emerging in cattle worldwide. It shares >50% sequence similarity with the human influenza C virus (HICV). Two clades of IDV are currently co-circulating in cattle herds… read more here.
Keywords: idv; human influenza; differential diagnosis; influenza viruses ... See more keywords
Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.77345
Abstract: During respiratory viral infections, the precise roles of monocytes and dendritic cells (DCs) in the nasopharynx in limiting infection and influencing disease severity are incompletely described. We studied circulating and nasopharyngeal monocytes and DCs in… read more here.
Keywords: blood nasopharynx; human influenza; infection; patterns monocyte ... See more keywords