A Bioinformatic Analysis of MicroRNAs' Role in Human Intervertebral Disc Degeneration.
Sign Up to like & getrecommendations! Published in 2019 at "Pain medicine"
DOI: 10.1093/pm/pnz015
Abstract: OBJECTIVES The aim of our study was to ascertain the underlying role of microRNAs (miRNAs) in human intervertebral disc degeneration (IDD). Design. Bioinformatic analysis from multiple databases. METHODS Studies of the association of miRNAs and… read more here.
Keywords: biological process; human intervertebral; process; intervertebral disc ... See more keywords
Expression of Glial Cell Line-Derived Neurotrophic Factor in the Human Intervertebral Disc.
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DOI: 10.1097/brs.0000000000003418
Abstract: STUDY DESIGN Biochemical and immunohistochemical analyses by the human intervertebral disc (IVD) cells and tissues. OBJECTIVE To examine the expression of glial cell line-derived neurotrophic factor (GDNF) and its receptors, GDNF family receptor (GFR) α1… read more here.
Keywords: expression; human ivd; ivd cells; human intervertebral ... See more keywords
Does Type II Diabetes Induce Early Senescence and Degeneration in Human Intervertebral Discs? A Tissue Biomarker Evaluation
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DOI: 10.14444/7045
Abstract: ABSTRACT Background: Diabetes mellitus is one of the leading causes of morbidity resulting in multi-organ dysfunction. Animal studies have shown that hyperglycemia results in stress-induced senescence through the p16-pRb pathway, thereby accelerating early disc degeneration.… read more here.
Keywords: senescence; human intervertebral; group; type diabetes ... See more keywords
Comparative metagenomic analysis of human intervertebral disc nucleus pulposus and cartilaginous end plates
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.927652
Abstract: Study design The diversity of microflora inhabiting endplate (EP) and nucleus pulposus (NP) tissues of human intervertebral disc (IVD) was profiled through NGS-supported 16S rRNA amplicon sequencing. Sixteen EP and their corresponding NP were excised… read more here.
Keywords: pulposus; abundance; ivd; human intervertebral ... See more keywords