Protocol to Generate Ureteric Bud Structures from Human iPS Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9021-4_10
Abstract: The generation of ureteric bud (UB), which is the renal progenitor that gives rise to renal collecting ducts and lower urinary tract, from human-induced pluripotent stem cells (hiPSCs) provides a cell source for studying the… read more here.
Keywords: generate ureteric; human ips; ureteric bud; structures human ... See more keywords
Scalable Measurements of Intrinsic Excitability in Human iPS Cell-Derived Excitatory Neurons Using All-Optical Electrophysiology
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2694-5
Abstract: Induced pluripotent stem (iPS) cells offer the exciting opportunity for modeling neurological disorders in vitro in the context of a human genetic background. While significant progress has been made in advancing the use of iPS… read more here.
Keywords: excitatory neurons; derived excitatory; cell derived; human ips ... See more keywords
Enrichment of high-functioning human iPS cell-derived hepatocyte-like cells for pharmaceutical research.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.01.019
Abstract: Human iPS cell-derived hepatocyte-like cells are expected to be utilized in pharmaceutical research. However, the purity of high-functioning hepatocyte-like cells is not high enough. In particular, the purity of cytochrome P450 3A4 (CYP3A4), which is… read more here.
Keywords: hepatocyte like; like cells; human ips; ips cell ... See more keywords
Induction of functional islet-like cells from human iPS cells by suspension culture
Sign Up to like & getrecommendations! Published in 2019 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2018.11.003
Abstract: Introduction To complement islet transplantation for type1 diabetic patients, cell-based therapy using pluripotent stem cells such as ES cells and iPS cells is promising. Many papers have already reported the induction of pancreatic β cells… read more here.
Keywords: suspension culture; ips cells; like cells; human ips ... See more keywords
Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101524
Abstract: SLC26A4 is the second most frequent gene implicated in congenital hearing loss after GJB2 mutations. Here, we report the generation of induced pluripotent stem cells (iPSCs), from a patient who was carrying a homozygous c.919-2A>G… read more here.
Keywords: cell line; human ips; patient carrying; ips cell ... See more keywords
Generation of human iPS cell line CBTCi001-A from dermal fibroblasts obtained from a healthy donor.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101630
Abstract: Human-induced pluripotent stem cell (hiPSC) CBTCi001-A line was generated from a healthy 30-year old male dermal fibroblasts using non-integrative reprogramming method using episomal-based plasmids expressing OCT4, SOX2, KLF4, and MYCL. Characterization of CBTCi001-A was confirmed… read more here.
Keywords: line; human ips; ips cell; cbtci001 ... See more keywords
Investigation of the usefulness of collagen peptide in intramyocardial injection of human iPS cell-derived cardiomyocytes
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.3700
Abstract: Injecting human induced pluripotent stem (iPS) cell-derived cardiomyocytes directly into the heart muscle holds promise as a treatment for heart failure. Achieving better engraftment is crucial for maximizing therapeutic effectiveness. Collagen peptide (CP) is a… read more here.
Keywords: derived cardiomyocytes; heart; injection; human ips ... See more keywords
Development of an evaluation method for addictive compounds based on electrical activity of human iPS cell‐derived dopaminergic neurons using microelectrode array
Sign Up to like & getrecommendations! Published in 2024 at "Addiction Biology"
DOI: 10.1111/adb.13443
Abstract: Addiction is known to occur through the consumption of substances such as pharmaceuticals, illicit drugs, food, alcohol and tobacco. These addictions can be viewed as drug addiction, resulting from the ingestion of chemical substances contained… read more here.
Keywords: addiction; derived dopaminergic; addictive compounds; human ips ... See more keywords
Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells
Sign Up to like & getrecommendations! Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.118.082123
Abstract: To develop a novel in vitro system for predicting intestinal drug absorption using human induced pluripotent stem (iPS) cell–derived intestinal epithelial cells, the cells need to have sufficient drug-metabolizing enzyme and drug transporter activities. We… read more here.
Keywords: epithelial cells; intestinal epithelial; human ips; differentiation human ... See more keywords
Development of a method of passaging and freezing human iPS cell-derived hepatocytes to improve their functions
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285783
Abstract: Human induced pluripotent stem (iPS) cell-derived hepatocyte-like cells (HLCs) are expected to replace primary human hepatocytes as a new source of functional hepatocytes in various medical applications. However, the hepatic functions of HLCs are still… read more here.
Keywords: ips cell; human ips; hlcs; method passaging ... See more keywords
In Vitro Gene Therapy Using Human iPS-Derived Mesoangioblast-Like Cells (HIDEMs) Combined with Microdystrophin (μDys) Expression as the New Strategy for Duchenne Muscular Dystrophy (DMD) Experimental Treatment
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252211869
Abstract: Duchenne Muscular Dystrophy (DMD) is a genetic disorder characterized by disruptions in the dystrophin gene. This study aims to investigate potential a therapeutic approach using genetically modified human iPS-derived mesoangioblast-like cells (HIDEMs) in mdx mouse… read more here.
Keywords: duchenne muscular; dystrophy dmd; dmd; human ips ... See more keywords