Protocol to Generate Ureteric Bud Structures from Human iPS Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9021-4_10
Abstract: The generation of ureteric bud (UB), which is the renal progenitor that gives rise to renal collecting ducts and lower urinary tract, from human-induced pluripotent stem cells (hiPSCs) provides a cell source for studying the… read more here.
Keywords: generate ureteric; human ips; ureteric bud; structures human ... See more keywords
Scalable Measurements of Intrinsic Excitability in Human iPS Cell-Derived Excitatory Neurons Using All-Optical Electrophysiology
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2694-5
Abstract: Induced pluripotent stem (iPS) cells offer the exciting opportunity for modeling neurological disorders in vitro in the context of a human genetic background. While significant progress has been made in advancing the use of iPS… read more here.
Keywords: excitatory neurons; derived excitatory; cell derived; human ips ... See more keywords
Enrichment of high-functioning human iPS cell-derived hepatocyte-like cells for pharmaceutical research.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.01.019
Abstract: Human iPS cell-derived hepatocyte-like cells are expected to be utilized in pharmaceutical research. However, the purity of high-functioning hepatocyte-like cells is not high enough. In particular, the purity of cytochrome P450 3A4 (CYP3A4), which is… read more here.
Keywords: hepatocyte like; like cells; human ips; ips cell ... See more keywords
Induction of functional islet-like cells from human iPS cells by suspension culture
Sign Up to like & getrecommendations! Published in 2019 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2018.11.003
Abstract: Introduction To complement islet transplantation for type1 diabetic patients, cell-based therapy using pluripotent stem cells such as ES cells and iPS cells is promising. Many papers have already reported the induction of pancreatic β cells… read more here.
Keywords: suspension culture; ips cells; like cells; human ips ... See more keywords
Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101524
Abstract: SLC26A4 is the second most frequent gene implicated in congenital hearing loss after GJB2 mutations. Here, we report the generation of induced pluripotent stem cells (iPSCs), from a patient who was carrying a homozygous c.919-2A>G… read more here.
Keywords: cell line; human ips; patient carrying; ips cell ... See more keywords
Generation of human iPS cell line CBTCi001-A from dermal fibroblasts obtained from a healthy donor.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101630
Abstract: Human-induced pluripotent stem cell (hiPSC) CBTCi001-A line was generated from a healthy 30-year old male dermal fibroblasts using non-integrative reprogramming method using episomal-based plasmids expressing OCT4, SOX2, KLF4, and MYCL. Characterization of CBTCi001-A was confirmed… read more here.
Keywords: line; human ips; ips cell; cbtci001 ... See more keywords
Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells
Sign Up to like & getrecommendations! Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.118.082123
Abstract: To develop a novel in vitro system for predicting intestinal drug absorption using human induced pluripotent stem (iPS) cell–derived intestinal epithelial cells, the cells need to have sufficient drug-metabolizing enzyme and drug transporter activities. We… read more here.
Keywords: epithelial cells; intestinal epithelial; human ips; differentiation human ... See more keywords
Development of a method of passaging and freezing human iPS cell-derived hepatocytes to improve their functions
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285783
Abstract: Human induced pluripotent stem (iPS) cell-derived hepatocyte-like cells (HLCs) are expected to replace primary human hepatocytes as a new source of functional hepatocytes in various medical applications. However, the hepatic functions of HLCs are still… read more here.
Keywords: ips cell; human ips; hlcs; method passaging ... See more keywords