Human Kidney‐Derived Cells Ameliorate Acute Kidney Injury Without Engrafting into Renal Tissue
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.16-0352
Abstract: Previous studies have suggested that CD133+ cells isolated from human kidney biopsies have the potential to ameliorate injury following intravenous (IV) administration in rodent models of kidney disease by integrating into damaged renal tissue and… read more here.
Keywords: medicine; renal tissue; human kidney; cd133 cells ... See more keywords
Ochratoxin A induces human kidney tubular epithelial cell apoptosis through regulating lipid raft/PTEN/AKT signaling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Toxicology"
DOI: 10.1002/tox.23308
Abstract: Ochratoxin A (OTA) is a fungal toxin that causes serious threat to human health. OTA could lead to the injury of various tissues, especially kidney injury. However, the toxic effects of OTA on human kidney… read more here.
Keywords: apoptosis; ota; human kidney; cell ... See more keywords
Growing a new human kidney
Sign Up to like & getrecommendations! Published in 2019 at "Kidney International"
DOI: 10.1016/j.kint.2019.04.040
Abstract: There are 3 reasons to generate a new human kidney. The first is to learn more about the biology of the developing and mature organ. The second is to generate tissues with which to model… read more here.
Keywords: growing new; medicine; kidney diseases; human kidney ... See more keywords
Effects of Polystyrene Microplastics on Human Kidney and Liver Cell Morphology, Cellular Proliferation, and Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03453
Abstract: Microplastics have gained much attention due to their prevalence and abundance in our everyday lives. They have been detected in household items such as sugar, salt, honey, seafood, tap water, water bottles, and food items… read more here.
Keywords: cell; liver; human kidney; liver cells ... See more keywords
Normothermic human kidney preservation drives iron accumulation and ferroptosis
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-61058-9
Abstract: Ex vivo normothermic machine perfusion has been proposed to protect deceased donor organs, promoting metabolic recovery and allowing quality assessment. However, its benefits for preserving deceased donor kidneys remain ambiguous. We postulate that the use… read more here.
Keywords: human kidney; iron accumulation; hemolysis; perfusion ... See more keywords
Volumetric, Nanoscale Optical Imaging of Mouse and Human Kidney via Expansion Microscopy
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28694-2
Abstract: Although light microscopy is a powerful tool for the assessment of kidney physiology and pathology, it has traditionally been unable to resolve structures separated by less than the ~250 nm diffraction limit of visible light. Here,… read more here.
Keywords: microscopy; volumetric nanoscale; mouse human; human kidney ... See more keywords
Geobiology reveals how human kidney stones dissolve in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-31890-9
Abstract: More than 10% of the global human population is now afflicted with kidney stones, which are commonly associated with other significant health problems including diabetes, hypertension and obesity. Nearly 70% of these stones are primarily… read more here.
Keywords: reveals human; kidney stones; geobiology reveals; human kidney ... See more keywords
Endoplasmic-reticulum-stress-induced lipotoxicity in human kidney epithelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfac041
Abstract: Accumulation of lipids and their intermediary metabolites under endoplasmic reticulum (ER) stress instigates metabolic failure, described as lipotoxicity, in the kidney. This study aimed to determine ER-stress-related sphingolipid and polyunsaturated fatty acid (PUFA) changes in… read more here.
Keywords: endoplasmic reticulum; stress; human kidney; reticulum stress ... See more keywords
Physiologic considerations of pig-to-human kidney xenotransplantation
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000858
Abstract: Purpose of review The greatest challenge facing end-stage kidney disease (ESKD) patients is the scarcity of transplantable organs. Advances in genetic engineering that mitigate xenogeneic immune responses have made transplantation across species a potentially viable… read more here.
Keywords: pig human; human kidney; physiologic considerations; considerations pig ... See more keywords
First porcine to human kidney transplantation performed in the United States.
Sign Up to like & getrecommendations! Published in 2021 at "Artificial organs"
DOI: 10.1111/aor.14139
Abstract: In an operation that lasted a little over 2 h, surgeons at New York University Langone Health transplanted a porcine kidney into a human patient without signs of early rejection. This is a landmark achievement… read more here.
Keywords: transplantation performed; porcine human; human kidney; kidney transplantation ... See more keywords
Thermal Analyses of a Human Kidney and a Rabbit Kidney During Cryopreservation by Vitrification.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4037406
Abstract: This study focuses on thermal analysis of the problem of scaling up from the vitrification of rabbit kidneys to the vitrification of human kidneys, where vitrification is the preservation of biological material in the glassy… read more here.
Keywords: human kidney; cryopreservation; rabbit kidney; vitrification ... See more keywords