The Human Laboratory and Drug Development in Alcohol Use Disorder: Recent Updates.
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DOI: 10.1007/978-1-4939-9554-7_12
Abstract: Despite a number of approved medications for alcohol use disorder (AUD), this chronic relapsing disease still produces a considerable global burden, with both health-related and financial consequences. While clinical trials are a critical step in… read more here.
Keywords: drug development; administration; drug; human laboratory ... See more keywords
Effects of naltrexone on alcohol self‐administration and craving: meta‐analysis of human laboratory studies
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DOI: 10.1111/adb.12425
Abstract: Randomized clinical trials have established the efficacy of naltrexone for reducing quantity of alcohol consumption and incidence of relapse to heavy drinking. To evaluate putative treatment mechanisms, human laboratory studies have examined naltrexone's effects on… read more here.
Keywords: self administration; alcohol self; human laboratory; laboratory studies ... See more keywords
Effects of varenicline and bupropion on laboratory smoking outcomes: Meta‐analysis of randomized, placebo‐controlled human laboratory studies
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DOI: 10.1111/adb.13218
Abstract: Human laboratory studies are widely used to evaluate behavioural mechanisms of pharmacotherapy effects. Results from human laboratory studies examining smoking cessation pharmacotherapies have not been examined in aggregate. The current meta‐analysis aimed to synthesize data… read more here.
Keywords: laboratory; meta analysis; randomized placebo; human laboratory ... See more keywords