Tumor suppression effect of targeting periostin with siRNA in a nude mouse model of human laryngeal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22622
Abstract: The incidence of laryngeal carcinoma is increasing, however, the mechanism is not fully understood. We aimed to investigate the efficacy of periostin gene silencing by siRNA on tumor inhibition, in a novel nude mouse model… read more here.
Keywords: nude mouse; laryngeal squamous; carcinoma; human laryngeal ... See more keywords
Long non-coding RNA biomarker for human laryngeal squamous cell carcinoma prognosis.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.05.046
Abstract: Long non-coding RNAs (lncRNA) were discovered in tumors. The regulation of lncRNA in human laryngeal squamous cell carcinoma (LSCC) remains incomplete. Uncovering the potential of lncRNA to stratify the prognosis of LSCC and streamline the… read more here.
Keywords: prognosis; squamous cell; long non; human laryngeal ... See more keywords
Expression and prognostic significance of YAP, TAZ, TEAD4 and p73 in human laryngeal cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Histology and histopathology"
DOI: 10.14670/hh-18-228
Abstract: OBJECTIVES The Hippo signaling pathway plays a critical role in organ size control and tissue homeostasis and its perturbation is associated with tumorigenesis. YAP (Yes associated protein) and TAZ (transcriptional co-activator with PDZ- binding motif)… read more here.
Keywords: expression; p73; yap; prognostic significance ... See more keywords
Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s148869
Abstract: Objective Beclin1 was previously found to be downregulated in human laryngeal cancer (LC) tissues, and it results in poor prognosis. This study aimed to further confirm the antitumor effects of Beclin1 in LC cell line… read more here.
Keywords: beclin1; overexpression beclin1; hep; proliferation ... See more keywords