Clinical and Mechanistic Implications of R-Loops in Human Leukemias
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DOI: 10.3390/ijms24065966
Abstract: Genetic mutations or environmental agents are major contributors to leukemia and are associated with genomic instability. R-loops are three-stranded nucleic acid structures consisting of an RNA–DNA hybrid and a non-template single-stranded DNA. These structures regulate… read more here.
Keywords: genomic instability; loops human; clinical mechanistic; human leukemias ... See more keywords