Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage
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DOI: 10.1038/s41467-021-22262-5
Abstract: Knowledge of genomic features specific to the human lineage may provide insights into brain-related diseases. We leverage high-depth whole genome sequencing data to generate a combined annotation identifying regions simultaneously depleted for genetic variation (constrained… read more here.
Keywords: human lineage; lineage; disease; brain ... See more keywords