A Biomimetic Human Lung‐on‐a‐Chip with Colorful Display of Microphysiological Breath
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202108972
Abstract: Lung‐on‐a‐chip models hold great promise for disease modeling and drug screening. Herein, inspired by the iridescence phenomenon of soap bubbles, a novel biomimetic 3D microphysiological lung‐on‐a‐chip system with breathing visualization is presented. The system, with… read more here.
Keywords: system; human lung; lung; lung chip ... See more keywords
Non-covalent interactions in the self-assembly of dihydropyridone supermolecules and in vitro anti-cancer assessment in human lung adenocarcinoma cell line (A549).
Sign Up to like & getrecommendations! Published in 2023 at "ChemPlusChem"
DOI: 10.1002/cplu.202200444
Abstract: The synthesis of dihydropyridone derivatives has been reported by ring rearrangement of pyrans using iodine and formic acid as a catalyst separately. Dihydropyridones were crystallized subjected for single-crystal X-ray crystallography to acquire their structural parameters.… read more here.
Keywords: self assembly; human lung; dihydropyridone supermolecules; non covalent ... See more keywords
Conductivity characteristics of human lung tissues
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Imaging Systems and Technology"
DOI: 10.1002/ima.22607
Abstract: In the treatment of lung cancer, bedside monitoring plays an important role. X‐ray computed tomography, as a mostly used technique, cannot provide medical surveillance for lung cancer patients in real‐time. In comparison, electrical impedance tomography… read more here.
Keywords: human lung; lung; conductivity; characteristics human ... See more keywords
The Novel mTOR Complex 1/2 Inhibitor P529 Inhibits Human Lung Myofibroblast Differentiation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25878
Abstract: Idiopathic pulmonary fibrosis is a progressive and deadly disorder with very few therapeutic options. Palomid 529 (8‐(1‐hydroxyethyl)‐2‐methoxy‐3‐(4‐methoxybenzyloxy)‐benzo[c]chromen‐6‐one; P529) is a novel dual inhibitor of mechanistic target of rapamycin complex 1/2 (mTORC1/2). In these studies, we… read more here.
Keywords: myofibroblast differentiation; human lung; tgf induced; p529 ... See more keywords
Isolation and Characterization of Human Lung Myeloid Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8570-8_9
Abstract: Multiparameter flow cytometry of human lungs allows for characterization, isolation, and examination of human pulmonary immune cell composition, phenotype, and function. Here we describe an approach to process lung tissues and then utilize a base… read more here.
Keywords: isolation characterization; immune cell; characterization human; human lung ... See more keywords
Transcriptome dynamics of alternative splicing events revealed early phase of apoptosis induced by methylparaben in H1299 human lung carcinoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02629-w
Abstract: Methylparaben is most frequently used as an antimicrobial preservative in pharmaceuticals and foods. Methylparaben has been subjected to toxicological studies owing to the increasing concern regarding its possible impact on the environment and human health.… read more here.
Keywords: phase; apoptosis; human lung; methylparaben ... See more keywords
Oleanolicacid-Chitosan Nanocomplex Induced Apoptotic Cell Death Through Mitochondrial Dysfunction in Human Lung Carcinoma: An Improved Synergetic Drug System for Cancer Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cluster Science"
DOI: 10.1007/s10876-020-01934-0
Abstract: Lung carcinoma is a forceful type of malignancy, having great elevated pace of morbidity and mortality with limited therapeutic options. The goal of current examination was to reveal the anticancer potential embedded in the oleanolic… read more here.
Keywords: lung carcinoma; human lung; chitosan nanocomplex; cancer ... See more keywords
A Multifunctional Hydrogel Delivers Gold Compound and Inhibits Human Lung Cancer Xenograft
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Research"
DOI: 10.1007/s11095-019-2581-z
Abstract: AbstractPurposeInterpenetrating network system (IPN), consisting of polyethylene glycol (PEG) –diacrylate (PEGdA) and modified gelatin, is a biocompatible and biodegradable hydrogel and has been studied for the local delivery of bioactive molecules and drugs. Gold(III) porphyrin(AuP)… read more here.
Keywords: hydrogel; cancer xenograft; human lung; lung cancer ... See more keywords
Mechanism of VIPR1 gene regulating human lung adenocarcinoma H1299 cells
Sign Up to like & getrecommendations! Published in 2019 at "Medical Oncology"
DOI: 10.1007/s12032-019-1312-y
Abstract: The vasoactive intestinal peptide receptor-1(VIPR1) has prominent growth effects on a number of common neoplasms. However, there were contradictions in the effect cross different cancers. We aimed to explore the effect of VIPR1 overexpression on… read more here.
Keywords: lung adenocarcinoma; vipr1; human lung; h1299 ... See more keywords
A SCID mouse‐human lung xenograft model of varicella‐zoster virus infection
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.08.012
Abstract: ABSTRACT Varicella pneumonia is one of the most serious, potentially life‐threatening complications of primary varicella‐zoster virus (VZV) infection in adults and immunocompromised individuals. However, studies on the lung pathogenesis of VZV infection as well as… read more here.
Keywords: microscopy; infection; lung; lung xenografts ... See more keywords
Hesperidin inhibits cell proliferation and induces mitochondrial-mediated apoptosis in human lung cancer cells through down regulation of β-catenin/c-myc
Sign Up to like & getrecommendations! Published in 2019 at "Biocatalysis and Agricultural Biotechnology"
DOI: 10.1016/j.bcab.2019.101065
Abstract: Abstract The aim of this study is to evaluate the mechanism of actions involved in the anticancer effect of hesperidin against cell proliferation and inducing apoptosis in human lung cancer A549 cells. MTT assay were performed,… read more here.
Keywords: human lung; cell proliferation; hesperidin; lung cancer ... See more keywords