Cultivation of Encapsulated Primary Human B Lymphocytes: A First Step towards a Bioartificial Germinal Center.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200256
Abstract: Polyelectrolyte microcapsules based on sodium cellulose sulfate (SCS) and poly-diallyl-dimethyl-ammonium chloride (PDADMAC) have previously been proposed as a suitable ex vivo microenvironment for the cultivation and differentiation of primary human T lymphocytes. Here, the same… read more here.
Keywords: cell; primary human; cultivation; human lymphocytes ... See more keywords
Chromosomal Aberration Test in Human Lymphocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9646-9_6
Abstract: Human peripheral lymphocytes (HPL) are non-cycling primary cells (G0 cells). They are easily collectable by venipuncture. In the presence of suitable culture media and stimulants in vitro HPL enter the cell cycle and divide mitotically.… read more here.
Keywords: aberration test; chromosomal aberration; biology; test human ... See more keywords
Genomic damage induced by the widely used fungicide chlorothalonil in peripheral human lymphocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.06.047
Abstract: Chlorothalonil is an important broad spectrum fungicide widely used in agriculture, silviculture, and urban settings. As a result of its massive use, chlorothalonil was found in all environmental matrices, with consequent risks to the health… read more here.
Keywords: used fungicide; induced widely; genomic damage; damage induced ... See more keywords
Imaging flow cytometry: A method for examining dynamic native FOXO1 localization in human lymphocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2018.01.001
Abstract: While flow cytometry can reliably assess surface and intracellular marker expression within small cell populations, it does not provide any information on protein localization. Several key transcription factors (TF) downstream of lymphocyte surface receptors are… read more here.
Keywords: localization human; native foxo1; foxo1; foxo1 localization ... See more keywords
In vitro genomic damage induced by urban fine particulate matter on human lymphocytes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65785-5
Abstract: Urban air pollution represents a global problem, since everyday many mutagenic and carcinogens compounds are emitted into the atmosphere, with consequent adverse health effects on humans and biota. Specifically, particulate matter air pollution was associated… read more here.
Keywords: genomic damage; air pollution; vitro genomic; particulate matter ... See more keywords
Investigation of genotoxic effects of paraben in cultured human lymphocytes
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2017.1414834
Abstract: Abstract Paraben is a phenolic derivative of benzoic acid extensively used as preservatives in food, pharmaceutical, and cosmetic industries due to its antimicrobial characteristics. The objective of this study was to evaluate the in vitro… read more here.
Keywords: 500 250; paraben; cells exposed; genotoxic effects ... See more keywords
Geraniol, a natural monoterpene, identifications of cytotoxic and genotoxic effects in vitro
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Essential Oil Research"
DOI: 10.1080/10412905.2021.1974581
Abstract: ABSTRACT Geraniol (GER) is an acyclic monoterpene alcohol. This study aimed to investigate the cytotoxic and genotoxic effect of GER in human lymphocytes using chromosomal aberrations (CAs) micronucleus (MN) assays and DNA damaging effect using… read more here.
Keywords: human lymphocytes; cytotoxic genotoxic; genotoxic effects; effect ... See more keywords
Combined chemotherapy and allogeneic human Vγ9Vδ2 T lymphocyte-immunotherapies efficiently control the development of human epithelial ovarian cancer cells in vivo
Sign Up to like & getrecommendations! Published in 2019 at "Oncoimmunology"
DOI: 10.1080/2162402x.2019.1649971
Abstract: ABSTRACT Epithelial ovarian cancer (EOC) represents 5% of human gynecologic cancers in the world, is heterogeneous and highly invasive with a dismal prognosis (5 year-survival rate read more here.
Keywords: chemotherapy; allogeneic human; ovarian cancer; human lymphocytes ... See more keywords
NKG2D Controls Natural Reactivity of Vγ9Vδ2 T Lymphocytes against Mesenchymal Glioblastoma Cells
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-19-0375
Abstract: Purpose: Cellular immunotherapies are currently being explored to eliminate highly invasive and chemoradioresistant glioblastoma (GBM) cells involved in rapid relapse. We recently showed that concomitant stereotactic injections of nonalloreactive allogeneic Vγ9Vδ2 T lymphocytes eradicate zoledronate-primed… read more here.
Keywords: gbm cells; glioblastoma; reactivity; nkg2d controls ... See more keywords
Toxicity of para-phenylenediamine (PPD;1, 4 diaminobenzene) on isolated human lymphocytes: The key role of intracellular calcium enhancement in PPD-induced apoptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Toxicology and industrial health"
DOI: 10.1177/07482337231176594
Abstract: Para-phenylenediamine (PPD) is a derivative of benzene used as an ingredient in dyes, a photographic developing agent, and a component of engineered polymers. The carcinogenicity of PPD, which has been documented in several studies, may… read more here.
Keywords: intracellular calcium; phenylenediamine ppd; ppd; human lymphocytes ... See more keywords
Genotoxicity of Glyphosate on Cultured Human Lymphocytes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Toxicology"
DOI: 10.1177/10915818211073514
Abstract: Glyphosate-based herbicides are the most used herbicides in the world. Despite being widely used, a dispute exists whether glyphosate-based herbicides have a negative effect on human health, particularly genotoxic effects. Therefore, the aim of this… read more here.
Keywords: glyphosate; cultured human; human lymphocytes; genotoxicity ... See more keywords