Elemental Mapping of Human Malignant Mesothelioma Tissue Samples Using High-Speed LA–ICP–TOFMS Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.1c04857
Abstract: This is the first report of the use of laser ablation–inductively coupled plasma time-of-flight mass spectrometry (LA–ICP–TOFMS) to analyze human malignant pleural mesothelioma (MPM) samples at the cellular level. MPM is an aggressive, incurable cancer… read more here.
Keywords: tissue; high speed; human malignant; icp tofms ... See more keywords
Hyperthermia induces therapeutic effectiveness and potentiates adjuvant therapy with non-targeted and targeted drugs in an in vitro model of human malignant melanoma
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DOI: 10.1038/s41598-018-29018-0
Abstract: In the present study, we have aimed to characterize the intrinsic, extrinsic and ER-mediated apoptotic induction by hyperthermia in an in vitro model of human malignant melanoma and furthermore, to evaluate its therapeutic effectiveness in… read more here.
Keywords: hyperthermia; therapeutic effectiveness; human malignant; malignant melanoma ... See more keywords
PO-365 Isothiocyanates as potent epigenetic regulators in human malignant melanoma chemoprevention
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.393
Abstract: Introduction Glucosinolates (GLs) are phytochemicals abundant in cruciferous vegetables, which are hydrolysed, by myrosinase, to a range of isothiocyanates (ITCs). These molecules are biologically active metabolites capable of mediating a plurality of anticancer effects including… read more here.
Keywords: melanoma; 365 isothiocyanates; human malignant; apoptotic induction ... See more keywords
Dickkopf-3 in Human Malignant Tumours: A Clinical Viewpoint
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DOI: 10.21873/anticanres.14617
Abstract: Dickkopf-3 (DKK3), also known as REIC, is a secreted glycoprotein. DKK3 is aberrantly expressed in various types of human malignant tumours. Promoter methylation status, intracellular protein expression, and protein expression in tumour vessels are significantly… read more here.
Keywords: human malignant; clinical viewpoint; tumours clinical; malignant tumours ... See more keywords
DNA methylation-mediated caspase-8 downregulation is associated with anti-apoptotic activity and human malignant glioma grade.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2017.2881
Abstract: The methylation-mediated silencing of tumor suppressors, including key apoptosis-related genes plays an important role in the pathogenesis and therapeutic resistance in human cancer. In this study, we aimed to elucidate the role and mechanisms of… read more here.
Keywords: methylation; glioma; malignant glioma; human malignant ... See more keywords
Biochanin A induces anticancer effects in SK-Mel-28 human malignant melanoma cells via induction of apoptosis, inhibition of cell invasion and modulation of NF-κB and MAPK signaling pathways
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DOI: 10.3892/ol.2017.6945
Abstract: The present study aimed to investigate the antitumor activity of Biochanin A in SK-Mel-28 human malignant melanoma cells. An MTT assay was used to study the cytotoxic effects of Biochanin A. In vitro wound healing… read more here.
Keywords: mel human; apoptosis; invasion; human malignant ... See more keywords
DHA induces apoptosis of human malignant breast cancer tissues by the TLR-4/PPAR-α pathways
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2017.7702
Abstract: Docosahexaenoic acid (DHA) oil is an important polyunsaturated fatty acid for the human body. Evidence has demonstrated that DHA is beneficial for inhibiting mammary carcinogenesis. However, the mechanisms of DHA mediating apoptosis induction have not… read more here.
Keywords: breast; malignant breast; dha oil; human malignant ... See more keywords
miR-340: A multifunctional role in human malignant diseases
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DOI: 10.7150/ijbs.51123
Abstract: MicroRNAs (miRNAs) are a class of short non-coding RNAs of approximately 22 nucleotides in length, which function by binding to the 3' UTR sequences of their target mRNAs. It has been reported that dysregulated miRNAs… read more here.
Keywords: human malignant; 340 multifunctional; role human; role ... See more keywords