Articles with "human metabolite" as a keyword



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Non‐clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR &agr;/&ggr; agonist, and its major human metabolite

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Published in 2017 at "Regulatory Toxicology and Pharmacology"

DOI: 10.1016/j.yrtph.2017.03.003

Abstract: &NA; The non‐clinical safety profile of aleglitazar, a peroxisome proliferator activated receptor alpha/gamma agonist, and its major human metabolite M6 was studied in a complete package consisting of drug metabolism and pharmacokinetics characterization, safety pharmacology,… read more here.

Keywords: human metabolite; safety; pharmacology; non clinical ... See more keywords