Human Metabotropic Glutamate Receptor 5 Antibodies Alter Receptor Levels and Behavior in Mice
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DOI: 10.1002/ana.26362
Abstract: Ophelia syndrome or encephalitis with antibodies against the metabotropic glutamate receptor 5 (mGluR5) manifests with behavioral changes, memory deficits, and anxiety. To study the antibody pathogenicity, mice received continuous cerebroventricular infusion of patients' or controls'… read more here.
Keywords: receptor antibodies; human metabotropic; glutamate receptor; metabotropic glutamate ... See more keywords