Generalized Hotelling's test for paired compositional data with application to human microbiome studies
Sign Up to like & getrecommendations! Published in 2018 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22127
Abstract: The human microbiome is a dynamic system that changes due to diseases, medication, change in diet, etc. The paired design is a common approach to evaluate the microbial changes while controlling for the inherent differences… read more here.
Keywords: test paired; hotelling test; generalized hotelling; human microbiome ... See more keywords
Impact of antibiotics on the human microbiome and consequences for host health
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1260
Abstract: It is well established that the gut microbiota plays an important role in host health and is perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial composition can have a negative impact on host… read more here.
Keywords: health; impact antibiotics; human microbiome; host health ... See more keywords
Processing and Analyzing Human Microbiome Data.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7274-6_31
Abstract: The human microbiome is associated with complex disorders such as diabetes, cancer, obesity and cardiovascular disorders. Recent technological developments have allowed researchers to fully quantify the composition of the microbiome using culture-independent approaches, resulting in… read more here.
Keywords: processing analyzing; human microbiome; microbiome; analyzing human ... See more keywords
The human microbiome, from Achilles armour to Nessus’ shirt
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Toxicology"
DOI: 10.1007/s00204-017-1951-8
Abstract: Neuman et al. 2015; O’Mahony et al. 2015; Sampson and Mazmanian 2015; Tralau et al. 2015). With a genome 100fold the size of ours this community harbours a non-redundant gene pool of at least 3.3… read more here.
Keywords: microbiome achilles; system; human microbiome; microbiome ... See more keywords
The P/N (Positive-to-Negative Links) Ratio in Complex Networks—A Promising In Silico Biomarker for Detecting Changes Occurring in the Human Microbiome
Sign Up to like & getrecommendations! Published in 2017 at "Microbial Ecology"
DOI: 10.1007/s00248-017-1079-7
Abstract: Relatively little progress in the methodology for differentiating between the healthy and diseased microbiomes, beyond comparing microbial community diversities with traditional species richness or Shannon index, has been made. Network analysis has increasingly been called… read more here.
Keywords: network; human microbiome; negative links; silico biomarker ... See more keywords
Human Microbiome in Health and Disease: The Good, the Bad, and the Bugly
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06059-y
Abstract: Ask a group of medical professionals and scientists what is the “hottest” area of investigation today, or to suggest a topic for a forum or symposium and the likely answer will be “the microbiome.” A… read more here.
Keywords: disease good; health disease; microbiome health; human microbiome ... See more keywords
Nature-based agriculture for an adequate human microbiome
Sign Up to like & getrecommendations! Published in 2020 at "Organic Agriculture"
DOI: 10.1007/s13165-020-00304-4
Abstract: In the discussion about food and the environment, most focus is on climate and nutrients. Food in relation to human health is an issue that gets much less attention. But what is healthy food and… read more here.
Keywords: nature based; agriculture; food; human microbiome ... See more keywords
GraphKKE: graph Kernel Koopman embedding for human microbiome analysis
Sign Up to like & getrecommendations! Published in 2020 at "Applied Network Science"
DOI: 10.1007/s41109-020-00339-2
Abstract: More and more diseases have been found to be strongly correlated with disturbances in the microbiome constitution, e.g., obesity, diabetes, or some cancer types. Thanks to modern high-throughput omics technologies, it becomes possible to directly… read more here.
Keywords: time evolving; human microbiome; analysis; time ... See more keywords
Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.01.001
Abstract: Summary The body-wide human microbiome plays a role in health, but its full diversity remains uncharacterized, particularly outside of the gut and in international populations. We leveraged 9,428 metagenomes to reconstruct 154,723 microbial genomes (45%… read more here.
Keywords: diversity; geography; human microbiome; extensive unexplored ... See more keywords
Strategies and advancements in human microbiome description and the importance of culturomics.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104460
Abstract: The human microbiota gained a big interest among the scientific community with numerous studies being performed to better understand its role in health and diseases. Even with all the success achieved in studying the bacterial… read more here.
Keywords: human microbiome; microbiome description; strategies advancements; description ... See more keywords
Priorities for the next 10 years of human microbiome research
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/d41586-019-01654-0
Abstract: The dream of microbiome-based medicine requires a fresh approach — an ecological and evolutionary understanding of host-microbe interactions — argues Lita Proctor.The dream of microbiome-based medicine requires a fresh approach — an ecological and evolutionary… read more here.
Keywords: medicine; human microbiome; microbiome research; years human ... See more keywords