Articles with "human microdose" as a keyword



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A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers

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Published in 2018 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.13476

Abstract: GSK3191607, a novel inhibitor of the Plasmodium falciparum ATP4 (PfATP4) pathway, is being considered for development in humans. However, a key problem encountered during the preclinical evaluation of the compound was its inconsistent pharmacokinetic (PK)… read more here.

Keywords: gsk3191607; drug gsk3191607; study antimalarial; human microdose ... See more keywords