LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "human microglial" as a keyword



Exploitation of microRNAs by Japanese Encephalitis virus in human microglial cells

Sign Up to like & get
recommendations! Published in 2018 at "Journal of Medical Virology"

DOI: 10.1002/jmv.24995

Abstract: JEV infection in CNS leads to the JE neuroinflammation. Children and old age individual have been reported to be more prone to JEV infection. MicroRNAs are endogenous, small non‐coding RNAs, which regulate the gene expression.… read more here.

Keywords: human microglial; exploitation micrornas; micrornas japanese; japanese encephalitis ... See more keywords

Tp47 induces cell death involving autophagy and mTOR in human microglial HMO6 cells.

Sign Up to like & get
recommendations! Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.04.013

Abstract: BACKGROUND Tp47 can induce immune cells to produce numerous inflammatory factors, some of which can trigger autophagy. Increased autophagy has a dual effect on cell survival. However, whether Tp47 induces autophagy in microglia is unknown.… read more here.

Keywords: death; human microglial; hmo6; cell death ... See more keywords

Alzheimer's Amyloid-β Accelerates Cell Senescence and Suppresses the SIRT1/NRF2 Pathway in Human Microglial Cells

Sign Up to like & get
recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/3086010

Abstract: Microglia play important roles in maintenance of brain homeostasis, while due to some pathological stimuli in aging-related neurodegenerative diseases including Alzheimer's disease, they are malfunctioning. Here, we demonstrated that amyloid-β (Aβ) accelerated cell senescence characterized… read more here.

Keywords: human microglial; sirt1 nrf2; microglial cells; senescence ... See more keywords

Urolithin A and nicotinamide riboside differentially regulate innate immune defenses and metabolism in human microglial cells

Sign Up to like & get
recommendations! Published in 2024 at "Frontiers in Aging Neuroscience"

DOI: 10.3389/fnagi.2024.1503336

Abstract: Introduction During aging, many cellular processes, such as autophagic clearance, DNA repair, mitochondrial health, metabolism, nicotinamide adenine dinucleotide (NAD+) levels, and immunological responses, become compromised. Urolithin A (UA) and Nicotinamide Riboside (NR) are two naturally… read more here.

Keywords: human microglial; nicotinamide riboside; urolithin nicotinamide; metabolism ... See more keywords

Erythropoietin Enhances Post-ischemic Migration and Phagocytosis and Alleviates the Activation of Inflammasomes in Human Microglial Cells

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2022.915348

Abstract: Recombinant human erythropoietin (rhEPO) has been shown to exert anti-apoptotic and anti-inflammatory effects after cerebral ischemia. Inflammatory cytokines interleukin-1β and -18 (IL-1β and IL-18) are crucial mediators of apoptosis and are maturated by multiprotein complexes… read more here.

Keywords: human microglial; post ischemic; migration phagocytosis; activation ... See more keywords
Photo from wikipedia

Comparative Analysis Identifies Similarities between the Human and Murine Microglial Sensomes

Sign Up to like & get
recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22031495

Abstract: One of the essential functions of microglia is to continuously sense changes in their environment and adapt to those changes. For this purpose, they use a set of genes termed the sensome. This sensome is… read more here.

Keywords: sensome; human microglial; analysis; microglial sensome ... See more keywords

Anti-Inflammatory Action of Dexmedetomidine on Human Microglial Cells

Sign Up to like & get
recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231710096

Abstract: Neuroinflammation, where inflammatory cytokines are produced in excess, contributes to the pathogenesis of delirium. Microglial cells play a central role in neuroinflammation by producing and releasing inflammatory cytokines in response to infection, tissue damage and… read more here.

Keywords: human microglial; inflammatory action; microglial cells; dex ... See more keywords

Human Microglia Models for NeuroHIV

Sign Up to like & get
recommendations! Published in 2025 at "Viruses"

DOI: 10.3390/v17050641

Abstract: Microglia are the primary target and reservoir of HIV infection in the central nervous system (CNS), which contributes to HIV-associated neurocognitive disorder (HAND). However, studying HIV infection of microglia has been challenged by the limited… read more here.

Keywords: human microglial; human microglia; microglia; microglia models ... See more keywords